• TRADE NAMES: Cervene; Revex (Baxter)
  • INDICATIONS: Reversal of opioid depression. Also used for alcohol dependence, impulse control disorders such as pathological gambling, pruritus of cholestasis.
  • CLASS: Antidote, Opioid antagonist
  • HALF-LIFE: 10.8 hours
  • CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
    Flumazenil

As an antidote, it is difficult to differentiate side effects due to the drug from those due to the effects of the poison.

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    DRUG REVIEW ARTICLE

    Click on the DRUG REVIEW ARTICLE tab (above) to see a review of nalmefene in the Taylor & Francis journal Expert Opinion on Drug Safety.

     

    (Note that non-subscribers to the journal will only be able to see an abstract of the article.)

Page last updated 07/31/2023

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Incidence

<1% 1‑5% 5‑10% 10‑15% 15‑20% 20‑30% >30%

Seriousness

Hospitalization possible
Life threatening
Fatal

Warnings in other populations

BreastfeedingBreast feeding

GeriatricGeriatric

PediatricPediatric