Penicillin and cephalosporins share a common beta-lactam structure. People who are allergic to penicillin are approximately 4 times more likely to develop an allergic reaction to a cephalosporin than those people who have no penicillin allergy (from 5–16% of patients allergic to penicillin develop reactions to cephalosporins).
- TRADE NAMES: Benaxona; Cefaxona; Cefaxone; Rocefin; Rocephalin; Rocephin (Roche); Tacex; Triaken; Zefone
- INDICATIONS: Various infections caused by susceptible organisms
- CLASS: Antibiotic, Antimicrobial, Antimicrobial, Cephalosporin, Cephalosporin; 3rd generation
- HALF-LIFE: 5–9 hours
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Aminoglycosides, Coumarins, Histamine H2 antagonists, Oral typhoid vaccine, Probenecid
- See adverse reactions attributed to class:
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Page last updated 08/07/2024
