Cefazolin
- TRADE NAMES: Ancef (GSK); Basocef; Cefacidal; Cefamezin; Elzogram; Gramaxin; Kefarin; Totacef; Zolin
- INDICATIONS: Various infections caused by susceptible organisms
- CLASS: Antibiotic, Antimicrobial, Cephalosporin, Cephalosporin; 1st generation
- HALF-LIFE: 1.4–1.8 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
BCG Vaccine, Phenytoin, Probenecid, Vitamin K antagonists
PREGNANCY CATEGORY: B
Safety and effectiveness in premature infants and neonates have not been established.
Penicillin and cephalosporins share a common beta-lactam structure. People who are allergic to penicillin are approximately 4 times more likely to develop an allergic reaction to a cephalosporin than those people who have no penicillin allergy (from 5–16% of patients allergic to penicillin develop reactions to cephalosporins).
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SKIN.
MUCOSAL.
CENTRAL NERVOUS SYSTEM.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
HEMATOLOGIC.
LOCAL.
RESPIRATORY.
OTHER.
Page last updated 10/14/2023
Symbol key
Incidence
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric