Search class reactions
Are you searching for an alternative drug within a class because your patient has suffered an allergic reaction to the one currently prescribed? Use the search class reaction tool to provide a quick guide to the drugs within the class to see if they are known to cause the reaction.
Select the class and at least one reaction to initiate your search. Results will update automatically as you add new reactions; there is no need to refresh the page. You may search up to six different reactions.
In the left hand column your results will show all the drugs within the selected class in the Litt’s Drug Eruption & Reaction Database. Each reaction will appear in subsequent columns. Where the drug has the reaction, the column will have Yes; if not, the column will have No. Where the reaction is also supported by evidential references in PubMed, the number of these in the database will appear in square brackets.
Drug names and positive results are hyperlinked to the relevant profile within the database. From the drug profile page you can also click directly through to any of the hyperlinked references for more information if required.
Reactions are hyperlinked to the relevant adverse reaction description page within the database so you can see other drugs which are known to cause the reaction.
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Class
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5-alpha reductase inhibitor 5-HT1 agonist 5-HT3 antagonist 5-HT4 agonist 5-Hydroxytryptamine antagonist Acetylcholine inhibitor Acetylcholinesterase inhibitor Adamantane Adenosine A2A receptor agonist Adenosine reuptake inhibitor Adenosine triphosphate-citrate lyase inhibitor Adrenergic alpha-receptor agonist Adrenergic alpha-receptor antagonist Adrenergic alpha2-receptor agonist Adrenergic beta-receptor agonist Adrenergic beta-receptor antagonist Aldosterone antagonist / mineralocorticoid receptor antagonist (MRA) Alfa-glucosidase Alkaloid Alkylating agent Alpha 1 adrenoreceptor antagonist Alpha adrenoceptor agonist Alpha-adrenergic channel blocker Alpha-galactosidase A (alpha-Gal A) pharmacological chaperone Alpha-glucosidase inhibitor Amebicide Amine alkaloid Amino acid Amino acid analog (synthetic) Amino sugar Aminolevulinate synthase 1-directed small interfering RNA Aminosalicylate Aminothiol AMPA glutamate receptor antagonist Amphetamine Amylinomimetic Anabolic steroid Analeptic Analgesic Analgesic; narcotic Analgesic; non-narcotic Analgesic; non-opioid Analgesic; opioid Analgesic; urinary Analog of sirolimus Anaplastic lymphoma kinase (ALK) inhibitor Androgen Androgen agonist Androgen antagonist Androgen receptor inhibitor Anesthetic Anesthetic; general Anesthetic; inhalation Anesthetic; local Angiogenesis inhibitor / antiangiogenic agent Angiopoietin-2 inhibitor Angiotensin receptor antagonist (blocker) Angiotensin receptor neprilysin inhibitor (ARNI) Angiotensin-converting enzyme (ACE) inhibitor Anion exchange resin Anthelmintic Anthroquinone glycoside Anti-attention deficit hyperactivity disorder (anti-ADHD) Anti-inflammatory Anti-inflammatory/analgesic agent Anti-interferon-gamma (IFNγ) monoclonal antibody Anti-interleukin-6 receptor monoclonal antibody Anti-ischemic Anti-Tumor Necrosis Factor-alpha (TNF-α antagonist) Antialcoholism Antiandrogen Antiarrhythmic Antiarrhythmic class Ia Antiarrhythmic class Ib Antiarrhythmic class Ic Antiarrhythmic class II Antiarrhythmic class III Antiarrhythmic class IV Antibacterial Antibiotic Antibiotic; aminoglycoside Antibiotic; anthracycline Antibiotic; beta-lactam Antibiotic; carbapenem Antibiotic; fluoroquinolone Antibiotic; glycopeptide Antibiotic; glycylcycline Antibiotic; lincosamide Antibiotic; lipoglycopeptide Antibiotic; macrolide Antibiotic; nitrofuran Antibiotic; nitroimidazole Antibiotic; oxazolidinone Antibiotic; penicillin Antibiotic; polymyxin Antibiotic; quinolone Antibiotic; rifamycin Antibiotic; streptogramin Antibiotic; sulfonamide Antibiotic; tetracycline Antibiotic; topical Antibody-drug conjugate (ADC) Anticholinergic Anticoagulant (antithrombotic) Anticoagulant glycoprotein Anticonvulsant Anticystine agent Antidepressant Antidepressant; tetracyclic Antidepressant; tricyclic Antidiabetic Antidiuretic hormone Antidiuretic hormone analog Antidote Antiemetic Antiepileptic Antiepileptic; hydantoin Antiepileptic; oxazolidinedione Antiepileptic; succinimide Antiepileptic; sulfonamide Antifibrinolytic Antifungal / antimycotic Antifungal; imidazole Antifungal; oxaborole Antifungal; triazole Antiglaucoma Antigonadotrophin Antihemorrhagic Antihypertensive Antihyperthyroid Antilipemic Antimalarial Antimetabolite Antimicrobial Antimitotic Antimotility Antimycobacterial (including antitubercular) Antimycobacterial; echinocandin Antineoplastic / anticancer agent (see also Immune checkpoint inhibitor) Antioxidant Antiplatelet (antithrombotic) Antiplatelet; cyclopentyl triazolo-pyrimidine (CPTP) Antiplatelet; thienopyridine Antiprolactin Antiprotozoal Antipsoriatic agent Antipsychotic Antipsychotic, atypical Antipyretic Antiretroviral Antisense oligomer Antisense oligonucleotide Antiseptic Antispasmodic Antithyroid Antithyroid; hormone modifier Antitussive Antiurilithic Antivenom Antiviral Antiviral; nucleoside analog Antiviral; nucleotide analog Antiviral; topical Anxiolytic Anxyolytic Aromatase inhibitor Barbiturate BCL-2 inhibitor Bcr-Abl tyrosine kinase inhibitor / (Breakpoint cluster region Abelson (Bcr-Abl) tyrosine kinase inhibitor Benzodiazepine Benzodiazepine antagonist Benzypyrone Beta adrenergic blocker Beta blocker Beta-2 adrenergic agonist Beta-3 adrenergic agonist Beta-lactamase inhibitor Biguanide Bile acid Bile acid sequestrant Bile acid transporter inhibitor Biologic Biologic disease-modifying antirheumatic drug (bDMARD) Bispecific CD19-directed CD3 T-cell engager Bisphosphonate Bone formation stimulant Bone resorption inhibitor Bradykinin B2 receptor antagonist BRAF inhibitor Bronchodilator Bruton’s tyrosine kinase (BTK) inhibitor Butyrophenone C. difficile toxin inhibitor C1 inhibitor Calcimimetic Calcineurin inhibitor Calcitonin gene-related peptide (CGRP) receptor antagonist Calcium channel blocker Cannabinoid Carbamoyl Phosphate Synthetase 1 (CPS 1) activator Carbonic anhydrase inhibitor Cardiac glycoside Cardio-stimulant Cardioprotective agent Cardiotonic agent Carminative Catechol-O-methyl transferase inhibitor Catecholamine CB1 Cannabinoid receptor antagonist CCR5 co-receptor antagonist CD19-directed antibody-drug conjugate CD20-directed cytolytic monoclonal antibody CD22-directed antibody-drug conjugate CD30-directed antibody-drug conjugate CD4-directed post-attachment HIV-1 inhibitor Cell death inducer Cell wall synthesis inhibitor Central muscle relaxant Cephalosporin Cephalosporin; 1st generation Cephalosporin; 2nd generation Cephalosporin; 3rd generation Cephalosporin; 4th generation Cephalosporin; 5th generation CFTR potentiator CFTR protein corrector Chelator Chelator, iron Chemical Chemotherapy modulating agent Chloride channel activator Cholesterol antagonist Cholesterol inhibitor Cholinesterase absorption inhibitor Cholinesterase inhibitor CNS depressant CNS stimulant Coagulant Coagulation factor VIII Coenzyme Q10 analog Colony stimulating factor Colony stimulating factor receptor 1 (CSF-1R) inhibitor Complement inhibitor Complement receptor antagonist Contrast agent Corticosteroid / Glucocorticoid Corticosteroid antagonist Corticosteroid, inhaled Corticosteroid, systemic Corticosteroid, topical Cortisol synthesis inhibitor Coumarin Covid-19 putative drug Covid-19 vaccine COX-2 inhibitor COX-2 selective inhibitor CTLA-4-blocking monoclonal antibody Cyclin-dependent kinase (CDK) 4/6 inhibitor Cyclodextrin CYP17 inhibitor CYP1A2 inducer CYP1A2 inhibitor CYP3A inhibitor CYP3A4 inducer CYP3A4 inhibitor Cytidine deaminase inhibitor Cytokine inhibitor Cytolytic Cytosine analog Depigmentation agent Depolarizing muscle relaxant Derivative of norethynodel Dermal filler Dextroamphetamine prodrug Diagnostic aid Dialysis solution Diarylquinoline Dietary supplement Dipeptidyl peptidase-4 (DPP-4) (gliptin) inhibitor Direct factor Xa inhibitor Direct-acting antiviral Disease-modifying antirheumatic drug (DMARD) Disinfectant Diuretic Diuretic, loop Diuretic, potassium-sparing Diuretic, thiazide DNA and RNA polymerase inhibitor Dopamine precursor Dopamine receptor agonist Dopamine receptor antagonist Dopamine reuptake inhibitor Drug-resistant antituberculosis agent Enactogen / emathogen Endothelin receptor (ETR) antagonist Enzyme Enzyme inhibitor Enzyme replacement Enzyme, glucocerebrosidase Ephedrine alkaloid Epidermal growth factor receptor (EGFR) inhibitor / antagonist Epithilone Ergot alkaloid Erythropoiesis-stimulating agent (ESA) Erythropoietin Estrogen Estrogen agonist Estrogen antagonist Estrogen receptor antagonist Eugeroic Exon skipping agent Factor IX stimulant Factor IXa- and factor X-directed antibody Farnesoid X receptor (FXR) agonist Farnesyltransferase inhibitor Fatty acid oxidation inhibitor Fibrate Fibrinolytic Fibroblast growth factor 23 (FGF23) blocking antibody Fibroblast growth factor receptor inhibitor Fluoropyrimidine Folate analogue Folate analogue metabolic inhibitor Folic acid antagonist Follicle-stimulating hormone Food additive Food supplement Fumaric acid ester Fusion protein GABA A receptor positive modulator GABA analog GABA receptor agonist Gabapentinoid Gadolinium-based contrast agent (GBCA) Gamma linoleic acid Ganglion blocker, peripheral GD2-binding monoclonal antibody Glucagon-like peptide-1 (GLP-1) receptor agonist Glucagon-like peptide-2 (GLP-2) analog Glucosylceramide synthase inhibitor Glycoaminoglycan Glycoprotein IIb/IIIa inhibitor Gonadotropin-releasing hormone (GnRH) agonist Gonadotropin-releasing hormone (GnRH) antagonist Growth hormone analog Growth hormone-releasing hormone analog Guanine nucleoside analog Guanosine nucleoside analog Guanylate cyclase stimulator Guanylate cyclase-C agonist Hallucinogen HCN channel blocker Heavy metal Hedgehog (Hh) signaling pathway inhibitor Hematopoietic Hemoglobin modulator Hemoglobin S (HbS) polymerization inhibitor Hemostatic Heparin antagonist Heparin, low molecular weight Heparinoid Hepatitis B virus necleoside analog reverse transcriptase inhibitor Hepatitis C virus non-nucleoside NS5B palm polymerase inhibitor Hepatitis C virus NS3/4A protease inhibitor Hepatitis C virus NS5A inhibitor Hepatitis C virus nucleotide analog NS5B polymerase inhibitor HER2-targeted antibody-drug conjugate HER2/neu receptor antagonist (HER2 receptor antagonist) Histamine H1 receptor antagonist Histamine H2 receptor antagonist Histamine H3 receptor antagonist Histamine H3 receptor inverse agonist Histone deacetylase (HDAC) inhibitor HIV cell fusion inhibitor HIV-1 protease inhibitor HMG-CoA reductase inhibitor / statin Hormone Hormone analog, polypeptide Hormone modulator Hormone, polypeptide Human insulin analog, long-acting Human thyroid stimulating hormone Hypnotic Hypnotic, non-benzodiazepine Hypoglycemic (antihyperglycemic) agent Hypoxia-inducible factor inhibitor IgE-targeting monoclonal antibody Imaging contrast medium Imidazole antithyroid agent Imidazoline receptor agonist Immune checkpoint inhibitor (incl. programmed death receptor-1 (PD-1) inhibitor) Immune stimulant Immunomodulator Immunosuppressant Incretin mimetic Indanedione Inotrope Inotropic sympathomimetic Insecticide Insulin analog Insulin secretagogue Insulin-like growth factor (IGF) Integrase strand transfer inhibitor Integrin receptor antagonist Interferon Interferon receptor antagonist Interleukin-1 inhibitor Interleukin-1 receptor antagonist (IL-IRa) Interleukin-12/23 antagonist Interleukin-17A (IL-17A) antagonist / interleukin-17 inhibitor Interleukin-2 Interleukin-2 receptor antagonist Interleukin-23 inhibitor Interleukin-4 receptor alpha antagonist Interleukin-5 antagonist Interleukin-6 (IL-6) antagonist Iodine-containing radiocontrast medium Iron supplement isocitrate dehydrogenase-1 inhibitor Isocitrate dehydrogenase-2 inhibitor Isoquinolone alkaloid Janus kinase (JAK) inhibitor Janus kinase-2 inhibitor Kallikrein inhibitor Keratinocyte growth factor Kinase inhibitor Laxative Leukotriene receptor antagonist Lipase inhibitor Lipid regulator Luteinizing hormone Lymphocyte function-associated antigen-1 (LFA-1) antagonist Macrolactam Macrolide immunosuppressant (derivative of sirolimus) Magnetic resonance imaging contrast medium Mast cell stabilizer Meglitinide MEK inhibitor (mitogen-activated protein kinase (MEK1 and MEK2) inhibitor) Melanocortin receptor agonist Melanocyte stimulating hormone A agonist Melatonin receptor agonist Membrane integrity antagonist MET (mesenchymal-epithelial transition) inhibitor / MET tyrosine kinase inhibitor Metalloproteinase inhibitor Methyltransferase inhibitor Microtubule inhibitor Miotic Mixed opioid agonist/antagonist Monoamine oxidase (MAO) inhibitor Monoamine oxidase B inhibitor Monoclonal antibody Mood stabilizer mTOR inhibitor Mucolytic Multikinase inhibitor Muscarinic antagonist Muscarinic cholinergic agonist Narcotic Natriuretic Neuraminidase inhibitor Neurokinin 1 receptor antagonist Neuroleptic Neuromuscular blocker Neuromuscular blocker (in ALS) Neuronal calcium channel blocker Neuroprotectant Neurotransmitter Nicotinic antagonist Nitrate Nitrosourea NMDA receptor antagonist Non-calcineurin inhibitor Non-depolarizing muscle relaxant Non-depolarizing neuromuscular blocker Non-nucleoside reverse transcriptase inhibitor Non-steroidal anti-inflammatory (NSAID) Nootropics Noradrenaline reuptake inhibitor Norepinephrine antagonist Norepinephrine reuptake inhibitor Nuclear export inhibitor Nucleoside analog reverse transcriptase inhibitor Nucleoside metabolic inhibitor Nucleotide analog reverse transcriptase inhibitor Oleoresin Oligonucleotide Oncolytic virus immunotherapy Ophthalmic agent, miotic Ophthalmic agent, toxin Opiate agonist Opiate agonist-antagonist Opioid agonist Opioid antagonist Opioid kappa receptor agonist Opioid mu receptor agonist Opioid receptor antagonist Opium alkaloid Optical imaging agent Orexin receptor antagonist Ornithine decarboxylase inhibitor Orthopoxvirus VP37 envelope wrapping protein inhibitor Oxytocic Pancreatic digestive enzyme supplement Parasiticide Parasympathomimetic Parathyroid hormone analog Parathyroid hormone antagonist Pediculocide Phenothiazine Phosphate binding agent Phosphodiesterase inhibitor Phosphodiesterase type 4 (PDE4) inhibitor Phosphodiesterase type 5 (PDE5) inhibitor Phosphoinositide 3-kinase (Phosphatidylinositol 3-kinase) (PI3K) inhibitor Phospholipase A2 inhibitor Phosphorothioate oligonucleotide Photoprotective Photosensitizer Phytoestrogen Pituitary hormone inhibitor Plasma kallikrein inhibitor Plasminogen activator Platelet aggregation inhibitor Platelet derived growth factor-BB Platelet-derived growth factor receptor alpha blocking antibody Platinum-based antineoplastic Pleuromutilin antibacterial Poly (ADP-ribose) polymerase (PARP) inhibitor Polymerase acidic (PA) endonuclease inhibitor Polypeptide Polypeptide hormone Pooled plasma (human), solvent/detergent treated Potassium binder Potassium channel activator Potassium channel antagonist Potassium channel blocker Potassium channel opener Proanthocyanadin Proanthocyanidin oligomer Probiotic Progesterone agonist Progestin/estrogen CHC Progestogen Progestogen antagonist Programmed death receptor-1 (PD-1) inhibitor Programmed death-ligand (PD-L1) inhibitor Prophylactic, urinary Proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor Prostacyclin receptor agonist Prostaglandin Prostaglandin analog Prostaglandin receptor agonist Protease-activated receptor-1 (PAR-1) antagonist Proteasome inhibitor Protein Protein analog Protein synthesis inhibitor Proton pump inhibitor (PPI) Protoporphyrin IX (PpIX) Psoralen Psychotomimetic Pulmonary surfactant Purine analog Pyridone Pyrimidine analog Pyrimidine synthesis inhibitor Pyruvate kinase activator Radioactive element Radiographic contrast medium Radiopharmaceutical Radiopharmaceutical, alpha-emitting Radiopharmaceutical, diagnostic agent RANK ligand (RANKL) inhibitor Ras–GTPase inhibitor Rauwolfia alkaloid Recombinant DNase Recombinant fusion protein Recombinant human granulocyte colony-stimulating factor Recombinant protein C Recombinant thrombopoeitin Renal dehydropeptidase inhibitor Renin inhibitor Repigmenting agent RET (Rearranged during Transfection) kinase inhibitor Retinoic acid receptors (RAR) agonist Retinoid Reversal agent for dabigatran Rho kinase inhibitor RNA polymerase inhibitor Rubefacient Salicylate Scabicide Sclerosant, local Sedative Selective estrogen receptor modulator (SERM) Selective norepinepherine reuptake inhibitor Selective relaxant binding agent Selective serotonin reuptake inhibitor (SSRI) Serine protease inhibitor Serotonin agonist Serotonin antagonist Serotonin receptor agonist Serotonin receptor antagonist Serotonin reuptake inhibitor Serotonin type 1A receptor agonist Serotonin type 1F receptor agonist Serotonin type 2A receptor antagonist Serotonin type 3 receptor antagonist Serotonin type 4 receptor agonist Serotonin-norepinephrine reuptake inhibitor Skeletal muscle relaxant Skeletal muscle relaxant, hydantoin Small interfering RNA (siRNA) Sodium channel antagonist Sodium-glucose co-transporter 2 (SGLT2) inhibitor ('gliflozin') Sodium-hydrogen exchanger 3 (NHE3) inhibitor Soluble guanylate cyclase (sGC) stimulator Somatostatin analog Sphingosine1-phosphate receptor modulator Spleen tyrosine kinase (Syk) inhibitor Steroid Stimulant Stimulant laxative Stimulant, mild Sulfonamide Sulfonylurea Survival motor neuron 2 (SMN2)-directed RNA splicing modifier Survival motor neuron-2 (SMN2)-directed antisense oligonucleotide Sweetening agent Sympathomimetic T-cell co-stimulation blocker T-cell co-stimulation modulator Taxane Thalidomide analog Thiazolidinedione Thienamycin Thiophosphate cytoprotective Thrombin inhibitor Thrombopoietin receptor (TPO) agonist Thymidine phosphorylase inhibitor Thymidine-based nucleoside analogue Thyroid hormone, synthetic TNF alpha agonist TNF modulator Tocolytic Topoisomerase 1 inhibitor Topoisomerase 2 inhibitor Trace element Transthyretin stabilizer Transthyretin-directed antisense oligonucleotide Transthyretin-directed small interfering RNA Trimonoamine modulator Triptan Tropomyosin receptor kinase inhibitor Tryptophan hydroxylase inhibitor Tyrosine catabolism inhibitor Tyrosine kinase inhibitor URAT1 inhibitor Urate oxidase Uricosuric Urolithic Vaccine Vascular endothelial growth factor (VEGF) inhibitor / antagonist Vascular stimulant Vasodilator Vasodilator, peripheral Vasopressin agonist Vasopressin receptor antagonist Vesicular monoamine transporter 2 inhibitor Vinca alkaloid Viral terminase complex inhibitor Vitamin Vitamin D analog Vitamin D receptor agonist Vitamin K Xanthine alkaloid Xanthine oxidase inhibitor
Reactions (up to six)
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Abdominal discomfort Abdominal distension Abdominal pain Abnormal dreams Abnormal hair growth Abnormal hair texture Abnormal vision Abrasion Abscess Acantholysis Acanthosis nigricans Accommodation disorder Acidosis (includes lactic acidosis) Acne (unspecified) Acne fulminans (acne maligna) Acne keloid Acne vulgaris ("acne") Acneiform eruption / acneiform dermatitis / acneiform rash Acneiform papular Acneiform pustular Acral desquamation Acral erythema Acral necrosis Acral purpura Acral sclerosis Acrodermatitis enteropathica Acromegaloid features Acromegaly Actinic granuloma Actinic keratoses Acute coronary syndrome Acute disseminated encephalomyelopathy Acute esophageal necrosis / black esophagus / Gurvits' syndrome Acute intermittent porphyria Acute respiratory distress syndrome Acute retinal necrosis Acute-on-chronic liver failure Acute-phase reaction Adermatoglyphia (fingerprint loss) Adrenal insufficiency (hypoadrenalism) Adrenalitis Adrenocorticotropic hormone (corticotropin; ACTH) deficiency Adrenocorticotropic hormone (corticotropin; ACTH) increased Adverse effects / adverse reactions Adverse fertility effect / decreased fertility / infertility AGEP Ageusia (taste loss) / taste disorder Aggression (includes anger) Agitation Agranulocytosis / severe selective neutropenia Air embolism Akathisia Akinetic mutism / mutism Alanine aminotransferase (ALT) increased Albuminuria Algospasm Alkaline phosphatase (ALP) increased Alkalosis Allergic reactions Allergic skin reactions Allodynia Alopecia / hair loss Alopecia areata Alopecia totalis Alopecia universalis Alveolar hemorrhage (pulmonary) Alveolitis Amblyopia Amenorrhea Amicrobial pustulosis of the folds Amnesia Amyloid-related imaging abnormalities (ARIA) Amyloidosis Amyotrophic lateral sclerosis Anagen effluvium Anaphylaxis Anemia Anetoderma Aneurysm Angina Angioedema (formerly named angioneurotic edema) Angiofibromatosis Angiogenesis Angiokeratoma Angioma Angiopathy Angular stomatitis Anhidrosis Anisocoria Anorectal discomfort Anorexia Anorgasmia Anosmia (smell loss) / smell disorder Anti-neutrophil cytoplasmic antibody (ANCA) vasculitis (angiitis) Anticoagulation Antiphospholipid antibody syndrome Antithyroid antibodies Anuria Anxiety Aortic dissection Aortitis / periaortitis Apathy Aphasia Aphthous stomatitis / aphthous ulcer / aphtha (aphthae) Aplasia cutis congenita Aplastic anemia Apnea Apparent mineralocorticoid excess Appendicitis Appetite decreased Appetite increased Application-site anesthesia Application-site bullae Application-site burning Application-site cellulitis Application-site dermatitis Application-site edema Application-site erythema Application-site exfoliation Application-site fixed eruption Application-site induration Application-site infection Application-site irritation Application-site pain Application-site pruritus Application-site reactions Application-site stinging Application-site vesicles Application-site xerosis Aquaresis Arachnoiditis Arm pain Arrhythmias Arterial occlusion Arterial thromboembolism Arteriosclerosis Arthralgia Arthritis / polyarthritis Arthropathy Ascites Aseptic meningitis Aspartate aminotransferase (AST) increased Asthenia Asthenopia Asthma Asystole Ataxia Atelectasis Atopic dermatitis Atrial fibrillation Atrial flutter Atrioventricular block Atrophic nails (onychatrophy) Atrophie blanche Atrophy / Skin atrophy Attention disturbances Autoimmune hepatitis Autoimmune Polyendocrine Syndrome Type 2 Autosplenectomy Azoospermia Azotemia Back pain Bacteremia Bacterial infection Balance disorder Balanitis Balanoposthitis Baller-Gerold syndrome Bartter-like syndrome Basal cell carcinoma Beading Beau's lines Behavioral disturbances / personality changes Behçet's disease Behçet's disease / Behçet's syndrome Bell's palsy (facial palsy) Benign prostatic hyperplasia Bicarbonate decreased Biliary colic Black bone disease Black stools / melena Black thyroid syndrome Black tongue / black hairy tongue (lingua villosa nigra) Blackwater fever Bladder cancer Bladder disorder Bleeding Blepharitis Blepharoconjunctivitis Blepharospasm Blindness Blood pressure variations Blue lunulae Blue toe syndrome / purple toe syndrome Bone loss / bone disorder Bone pain / joint pain Bone tumor Borborygmus (bowel sounds) Bowel complications Bradyarrhythmia Bradycardia / sinus bradycardia Bradykinesia Bradyphrenia Bradypnea / respiratory rate decreased Brain abscess Brain atrophy / cerebral atrophy / cerebellar atrophy Brainstem dysgenesis BRASH syndrome Breast abscess Breast atrophy Breast cancer Breast disorder / breast discomfort Breast hypertropy / gigantomastia / macromastia Breast pain (mastalgia) Breast swelling Breast tenderness Brittle hair Brittle nails Bromhidrosis Bronchiectasis Bronchiolitis Bronchitis Bronchospasm Brugada syndrome Bruise / bruising / contusion / ecchymosis (ecchymoses) Bruxism (teeth grinding) Bullae Bullous acral erythema Bullous dermatosis Bullous hemorrhagic dermatosis Bullous impetigo Bullous lichen planus Bullous pemphigoid / pemphigoid Bullous skin rash Bundle branch block Burning / skin burning sensation Burning Mouth Syndrome / glossodynia / glossalgia / glossopyrosis Buschke–Lowenstein penile carcinoma Butterfly eruption on the face C-reactive protein (CRP) increased Café-au-lait macules Calcinosis cutis / calcification Callus Cancer Candidal vaginitis Candidiasis / candidosis Capillaritis Capillary leak syndrome Carcinoma Carcinosarcoma Cardiac arrest Cardiac disorder / cardiac dysfunction Cardiac failure Cardiac tamponade Cardiogenic shock Cardiomyopathy Cardiotoxicity Cardiovascular adverse effect (includes major adverse cardiovascular events (MACE)) Carotenemia Carotid artery dissection Carotidynia Carpal tunnel syndrome Cataplexy Cataract Catatonia Catheter-related complication Catheter-related infection Celiac disease / coeliac disease Cellulitis and pseudocellulitis Central anticholinergic syndrome Central pontine myelinolysis Cerebellar degeneration Cerebellar syndrome Cerebellitis Cerebral edema / brain edema Cerebral hemorrhage Cerebral ischemia Cerebral vasculitis (angiitis) Cerebral venous sinus thrombosis Cerebrovascular adverse event Cervical dystonia / antecollis / spasmodic torticollis Cervical stenosis Chalazion / Chalazia (eyelid cyst) Charles Bonnet syndrome Cheilitis (inflammation of the lips) Chest discomfort Chest pain Chest wall rigidity Chiasmal neuritis Chills Chloasma Cholangiopathy Cholangitis / sclerosing cholangitis Cholecystitis Cholecystolithiasis (gallstones in the gall bladder) Choledocholithiasis (bile duct stones / gallstones in the bile duct) Cholelithiasis (gallstones in the gall bladder or the bile duct) Cholestasis Cholestatic liver injury / cholestatic hepatitis Cholesteatoma (middle ear) Chondritis Chondrolysis Chorea Choreoathetosis Chorioretinitis / choroiditis Chorioretinopathy Choroidal detachment Choroidal lesions Chromatopsia Chromaturia Chromhidrosis Chrysiasis Churg-Strauss syndrome Chylothorax Cicatricial pemphigoid Circulatory collapse Clammy skin Clostridium difficile colitis CNS adverse reaction CNS depression Coagulopathy Coarse facies Coarsening of skin Cobblestone papillae Cognitive impairment Cold allodynia / cold sensitivity / cold intolerance Cold extremities Cold microabscesses Cold urticaria Colitis Collagen disease Collodion-like skin Coma Compartment syndrome Compulsions / obsessive-compulsive symptoms Condylomata acuminata (genital warts) Confusion Congenital malformations Congestive heart failure Conjugated bilirubin increased / direct bilirubin increased Conjunctival edema Conjunctival erythema Conjunctival hemorrhage Conjunctival hyperemia / conjunctival injection Conjunctival pigmentation Conjunctival redness Conjunctival ulceration Conjunctivitis (conjunctival inflammation) Constipation Contact dermatitis Convulsions COPD Cornea verticillata / vortex keratopathy / whorl keratopathy Corneal abnormalities Corneal deposits Corneal dysplasia Corneal edema Corneal erosion Corneal infiltrates Corneal melting Corneal opacity Corneal perforation Corneal scarring Corneal staining Corneal ulceration Coronary arteriospasm Coronary spasm Coronary spastic angina Coronary vasospasm Cotton wool spots Cough Cramps Cranial neuropathy Creatine phosphokinase (CPK) / creatine kinase increased (hyperCKemia) Crohn's disease Crusting Cryoglobulinemia Crystal (crystalline) arthritis / pseudogout / calcium pyrophosphate deposition Crystal precipitation Crystalluria Curly hair Cushing's syndrome Cushingoid features Cutaneous adverse reaction Cutaneous collagenous vasculopathy Cutaneous polyarteritis nodosa Cutaneous toxicity / skin toxicity Cutis laxa / elastolysis Cyanopsia Cyanosis / acrocyanosis Cyst / pseudocyst Cystitis (includes interstitial cystitis / bladder pain syndrome) Cytogenetic abnormalities Cytokine release syndrome / cytokine storm Cytomegalovirus infection Cytopenia Dandruff / pityriasis capitis Dapsone syndrome Darier's disease / keratosis follicularis Death Decreased consciousness Deepening of upper lid sulcus Defecation Dehydration Delirium Delusions Delusions of parasitosis Dementia Demyelinating neuropathy / demyelination Dental disease Depersonalization Depigmentation Depression Dermatitis Dermatitis herpetiformis Dermatofibromas Dermatofibrosarcoma protuberans Dermatomyositis Dermographism / dermographic urticaria (chronic inducible urticaria) / urticaria factitia Desquamation Diabetes insipidus Diabetes mellitus Diabetes mellitus inadequate control Diabetic ketoacidosis Diaper rash Diaphoresis Diarrhea Differentiation syndrome Digital ischemia Digital malformations Digital necrosis Digitalis intoxication Dilated pupils Diplopia (double vision) Dipsia (thirst) / polydipsia Discoloration / nails (dyschromia) Discoloration / skin (dyschromia) Disorientation Disseminated histoplasmosis Dissociation (psychology) Disulfiram-like reaction Diverticular disease Downbeat nystagmus DRESS syndrome (Drug-induced hypersensitivity syndrome) Dropped-head syndrome Drug-induced disease (Cardiovascular) Drug-induced disease (Central Nervous System) Drug-induced disease (Gastrointestinal/Hepatic) Drug-induced disease (Genitourinary) Drug-induced disease (Hair) Drug-induced disease (Mucosal) Drug-induced disease (Nails) Drug-induced disease (Ocular) Drug-induced disease (Renal) Drug-induced disease (Respiratory) Drug-induced disease (Skin) Dry eye (keratoconjunctivitis sicca) Dry hair Dry mucous membranes Dry skin Dry throat Duodenitis Dysarthria Dyschromatopsia Dysesthesia Dysgeusia Dyshidrosis Dyskinesia Dyslipidemia Dysmenorrhea Dyspareunia Dyspepsia / functional dyspepsia / gastroparesis (indigestion) Dysphagia Dysphasia Dysphonia Dysphoria Dyspnea / shortness of breath Dysrhythmia Dystonia Dysuria Ear infection Ear pain Eccrine hidrocystomas Eccrine squamous syringometaplasia Eclampsia Ecthyma Ecthyma gangrenosum Ectropion / cicatricial ectropion Eczema / eczematous reaction / eczematous eruption Eczema herpeticum Eczema vaccinatum Edema / fluid retention Edema of lip Ehlers–Danlos syndrome Ejaculatory dysfunction Elastosis perforans serpiginosa Electrocardiography changes Electrolyte imbalance / electrolyte disorder / electrolyte abnormalities / dyselectrolytemia Elevated plasma D-dimer level Elkonyxis Embolia cutis medicamentosa (Nicolau syndrome) / livedoid dermatitis Emotional lability Emphysema Encephalitis Encephalomyelitis Encephalopathy Endocrine-related adverse effect / endocrinopathy Endometrial cancer Endometrial hyperplasia Endometrial polyp Endophthalmitis Enteritis Enterocolitis Enteropathy Enuresis (urinary incontinence) Eosinophilia Eosinophilia–myalgia syndrome Eosinophilic cellulitis / Wells' syndrome Eosinophilic fasciitis Eosinophilic gastrointestinal disorders Eosinophilic myocarditis Eosinophilic pneumonia Eosinophilic pustular folliculitis Eosinophilic tracheitis Eosinophillic pleural effusion Ephelides (freckles) Epidermolysis bullosa Epidermolysis bullosa acquisita Epididymitis Epigastric discomfort Epilepsy Epiphora Epiploic appendagitis Epiretinal membrane formation Episcleritis Epistaxis Erectile dysfunction Erection Erosio interdigitalis blastomycetica Erosion of psoriatic plaques Erosions Erosive pustular dermatosis Eructation (belching) Eruptive facial cyst Erysipelas Erythema Erythema annulare Erythema annulare centrifugum Erythema dyschromicum perstans / ashy dermatosis Erythema gyratum repens Erythema multiforme Erythema necrolyticum migrans Erythema nodosum Erythroderma Erythroid hypoplasia Erythromelalgia / erythermalgia Erythropoiesis Erythrosis Esophageal achalasia / achalasia Esophageal dysmotility Esophageal perforation Esophageal stenosis Esophagitis Esotropia Euglycemic diabetic ketoacidosis Euphoria / elation Evans' syndrome Exanthems Excoriations Exfoliation Exfoliative dermatitis Exfoliative erythroderma Exophthalmos Extrapyramidal symptoms Extrasystoles Extravasation Eyebrow madarosis Eyebrow ptosis / brow ptosis Eyelash changes Eyelashes – hypertrichosis Eyelashes – madarosis Eyelashes – pigmentation Eyelashes – ptosis Eyelid burning Eyelid crusting Eyelid dermatitis Eyelid dermatochalasis Eyelid eczema Eyelid edema / palpebral edema / blepharedema Eyelid erythema Eyelid granuloma Eyelid irritation Eyelid necrosis Eyelid pain Eyelid pigmentation Eyelid pruritus Eyelid ptosis / blepharoptosis Eyelid stinging Eyelid twitching / eyelid myokymia Eyelid xerosis Facial asymmetry Facial burning Facial edema Facial erythema Facial flushing Facial numbness Facial rash Facial scarring Facial skin hyperpigmentation Facial xerosis Fall Fanconi syndrome Fasciitis Fat distribution abnormality Fat embolism Febrile neutropenia Fecal incontinence Fecal urgency Fecaloma Feces discolored Ferritin levels increased Fetal adverse effect Fetal heart rate alteration Fetal hydantoin syndrome Fetotoxicity Fever (pyrexia) (includes hyperpyrexia) Fibroadenoma Fibromyalgia Fibrosing colonopathy Fibrosis Finger clubbing Fissures Fistula Fixed eruption / fixed drug eruption Flagellate dermatitis Flagellate erythema/pigmentation Flaking Flatulence Floppy iris syndrome Flushing / rubefaction Foamy urine Folic acid (folate) deficiency / vitamin B9 deficiency / hypofolatemia Follicular dermatitis Follicular keratosis Follicular mucinosis Follicular pustular eruption Folliculitis Folliculitis decalvans Food aversion Foot ulceration Forehead swelling Foreign body sensation Formication Fox–Fordyce disease Fractures Frostbite Fulminant diabetes Fundic gland polyposis Fungal dermatitis Furunculosis Gait instability / postural instability Galactorrhea Gamma glutamyl transpeptidase (GGT) increased Gangrene Gasping syndrome Gastric adenocarcinoma / gastric cancer Gastric antral vascular ectasia (GAVE) Gastric mucosal injury Gastritis / pangastritis / gastric irritation Gastroenteritis Gastroesophageal reflux Gastrointestinal adverse reaction Gastrointestinal bleeding Gastrointestinal disorder / discomfort Gastrointestinal fistula Gastrointestinal hemorrhage Gastrointestinal hypomotility Gastrointestinal obstruction / gastrointestinal stricture Gastrointestinal perforation / perforated colon / gastric perforation Gastrointestinal ulceration Generalized edema (includes anasarca) Generalized eruption Genital bullous pemphigoid Genital edema Genital mycotic infection Genital pruritus Genital ulceration Genitourinary infection / genital infection / reproductive tract infection Gianotti–Crosti syndrome Gingival bleeding Gingival hyperplasia / gingival hypertrophy / gingival enlargement / gingival overgrowth Gingival lesions Gingival lichenoid reaction Gingival necrosis Gingival pigmentation Gingival ulceration Gingivitis Gingivostomatitis Glanzmann thrombasthenia Glaucoma Glomerular filtration rate decreased Glomerulonephritis Glomerulosclerosis (focal segmental glomerulosclerosis) Glossitis (inflammation of the tongue) Glucagonoma syndrome Glucose dysregulation Glucose intolerance Glycosuria Gout Gouty tophi Graft dysfunction Graft-versus-host reaction Granulation tissue Granulocytopenia Granuloma annulare Granulomas Granulomatous reaction Graves' disease Green breast milk Green urine Grinspan's syndrome Growth retardation Guillain-Barré syndrome / acute inflammatory demyelinating polyradiculoneuropathy Gut microbiome / gut microbiota / gastrointestinal microbiota changes / disturbance Gynecomastia Gyrate erythema Hair changes Hair color changes Hair disorder Hair pigmentation Halitosis Hallucinations Hallucinations, auditory Hallucinations, olfactory Hallucinations, visual Halo dermatitis Halogenoderma Hand deformity Hand–foot syndrome (palmar–plantar erythrodysesthesia) Harlequin syndrome Headache Hearing impairment Hearing loss (hypoacusis) Heart block Heart rate alteration Heel pad thickening Hemagglutination Hemarthrosis (articular bleeding) Hematemesis Hematocrit (packed cell volume (PCV)) increased Hematological adverse effect Hematoma Hematuria Hemianopsia Hemoglobin decreased Hemoglobin increased Hemolysis Hemolytic anemia Hemolytic uremic syndrome Hemophagocytic lymphohistiocytosis / hemophagocytic syndrome Hemophilia Hemoptysis Hemorrhage Hemorrhagic colitis Hemorrhagic gastritis Hemorrhoids Hemospermia Hemothorax Hemotoxicity Henoch-Schönlein purpura / IgA vasculitis / immunoglobulin A vasculitis Hepatic (liver) disorder / hepatobiliary disorder / hepatic (liver) dysfunction Hepatic failure Hepatic hemorrhage Hepatic sarcoidosis Hepatic steatosis Hepatitis Hepatomegaly Hepatotoxicity / liver injury / acute liver injury / drug-induced liver injury (DILI) Hernia Herpes Herpes genitalis Herpes gestationis Herpes simplex Herpes zoster Herpetic whitlow Hiccups / singultus Hidradenitis suppurativa (acne inversa) High-density lipoprotein (HDL) increased Hirsutism Histiocytoma Hoarseness Hodgkin's disease Hoigne's syndrome Hormone deficiency Horner's syndrome Hostility Hot flashes / hot flushes Human papilloma virus reactivation Hyperactivity Hyperacusis Hyperalgesia Hyperammonemia Hyperamylasemia Hyperbilirubinemia Hypercalcemia Hypercalciuria Hyperchlorhydria Hypercholesterolemia Hyperesthesia Hypergastrinemia Hyperglycemia (includes glucose increased) Hyperhidrosis Hyperkalemia Hyperkeratosis Hyperkinesia Hyperkinesia Hyperlactatemia Hyperlipasemia Hyperlipidemia Hypermagnesemia Hypermagnesiuria Hypermelanosis Hypernatremia Hyperostosis Hyperoxaluria Hyperparathyroidism Hyperphosphatemia Hyperpigmentation Hyperprogression (accelerated tumor growth after initiation of immunotherapy) Hyperprolactinemia Hyperreflexia Hypersensitivity Hypersexuality Hypersomnia Hypertension Hyperthermia Hyperthyroidism Hypertonia Hypertransaminasemia (hepatic transaminitis) / elevated transaminases Hypertrichosis Hypertriglyceridemia (includes triglycerides increased) Hypertrophic lipodystrophy Hypertrophic osteoarthropathy (Pierre Marie-Bamberger syndrome) Hypertrophy Hyperuricemia Hyperventilation Hypervigilance Hypervolemia (fluid overload) Hyphema Hypoalbuminemia / albumin decreased Hypoalphalipoproteinemia Hypocalcemia Hypocortisolism Hypocupremia Hypoesthesia (numbness) Hypofibrinogenemia Hypogammaglobulinemia Hypogeusia Hypoglycemia Hypogonadism Hypohidrosis Hypokalemia Hypokinesia Hypoleptinemia Hypomagnesemia Hypomania Hypomelanosis Hyponatremia Hyponychial dermatitis Hypoparathyroidism Hypophosphatemia Hypophysitis Hypopigmentation Hypopituitarism Hypoplasia of phalanges Hypoproteinemia Hypoprothrombinemia Hypopyon Hyporeflexia Hyposmia / smell disorder Hyposomnia Hypotension Hypothermia Hypothyroidism Hypotonia Hypotony Hypotrichosis Hypouricemia Hypovitaminosis Hypovolemia Hypoxemia Hypoxia Ichthyosis Icteric sclera Id reaction Idiosyncratic drug reactions Ileitis Ileocolitis (see also colitis and ileitis) Ileus / adynamic ileus / paralytic ileus IM3OS Immune Reconstitution Inflammatory Syndrome Immune-related adverse effect Immunoglobulin A (IgA) nephropathy (Berger's disease) Immunosupression Impaired concentration Impetigo Impotence Impulse control disorder / impulsivity / drug-induced impulsivity Inappropriate secretion of antidiuretic hormone (SIADH) Incontinenti pigmenti Incoordination Induration Infection Infective pulmonary exacerbation of cystic fibrosis Inflammation Inflammatory arthritis Inflammatory bowel disease Inflammatory papules Influenza Influenza- ('flu)-like syndrome Infusion-related reactions Infusion-site erythema Infusion-site granuloma Infusion-site irritation Infusion-site pain Infusion-site rash Infusion-site reactions Ingrown Injection-site abscess Injection-site alopecia Injection-site atrophy Injection-site bleeding Injection-site bruising Injection-site bullous eruption Injection-site burning Injection-site calcification Injection-site cancer Injection-site cellulitis Injection-site coldness Injection-site dermatitis Injection-site desquamation Injection-site discomfort Injection-site ecchymoses Injection-site eczematous eruption Injection-site edema Injection-site erythema Injection-site exanthems Injection-site extravasation Injection-site fibrosis Injection-site gangrene Injection-site granuloma Injection-site hematoma Injection-site hemorrhage Injection-site hypersensitivity Injection-site induration Injection-site infection Injection-site inflammation Injection-site irritation Injection-site lichenoid reaction Injection-site lipoatrophy/lipohypertrophy Injection-site lymphoma Injection-site mass Injection-site necrosis Injection-site nodules Injection-site numbness Injection-site pain Injection-site panniculitis Injection-site papules and nodules Injection-site paralysis Injection-site phlebitis Injection-site pigmentation / injection-site discoloration Injection-site piloerection and vasoconstriction Injection-site plaques Injection-site pruritus Injection-site purpura Injection-site pyoderma Injection-site reaction Injection-site scarring Injection-site scleroderma Injection-site swelling Injection-site tenderness Injection-site thrombophlebitis Injection-site thrombosis Injection-site ulceration Injection-site urticaria Injection-site varicella-like eruption Injection-site vasculitis (angiitis) Injection-site vesicular eruption Insomnia Insulin allergy Insulin autoimmune syndrome / insulin autoimmune hypoglycemia / Hirata's disease Insulin resistance Interstitial lung disease / interstitial pneumonitis / interstitial pneumonia (cryptogenic organizing pneumonia) / drug-induced interstitial lung disease Intertrigo Intestinal angioedema Intestinal bleeding Intestinal lymphangiectasia / intestinal lymphangiectasis Intestinal necrosis Intestinal pseudo-obstruction (Ogilvie syndrome) Intoxication Intra-abdominal abscess Intracardiac thrombus Intracranial hemorrhage Intracranial pressure decreased Intracranial pressure increased (intracranial hypertension) Intraocular hypertension Intraocular inflammation Intraocular pressure increased Intraventricular hemorrhage Intussusception Iododerma Iridocyclitis Iris neovascularization Iris pigmentation Iritis Irritability Irritation (skin) Ischemic injury Ischemic stroke / cerebral infarction Jadassohn–Borst epithelioma Jarisch–Herxheimer reaction Jaundice Jaw pain Jittery feelings Joint disorder Joint effusion Joint pains Kaposi's sarcoma Kaposi's varicelliform eruption Kawasaki syndrome Keloid Keratitis (ocular keratitis) Keratoacanthoma (Grzybowski syndrome) Keratoconjunctivitis Keratoderma Keratolysis exfoliativa Keratopathy Keratoses Keratosis pilaris Keratouveitis Ketonuria Koebner phenomenon Koilonychia Kounis syndrome / allergic angina syndrome / allergic myocardial infarction Lacrimal duct stenosis / punctal stenosis Lacrimation Lactate dehydrogenase levels increased Lactate dehydrogenase levels reduced Lactation Lambert-Eaton myasthenic syndrome Large-vessel vasculitis Laryngeal injury Laryngismus Laryngitis Laryngospasm (laryngeal dystonia / spasmodic dysphonia) Leg cramps Leg pain Leg swelling Leg ulceration Legionellosis Lens opacity Lentigo (lentigines; lentigos (pl)) Leprosy Lesions Leukemia Leukocytoclastic vasculitis (angiitis) Leukocytopenia (leukopenia) / leukocytes (white blood cells) decreased Leukocytosis (elevated white blood cell (WBC) count) Leukoderma Leukoencephalopathy / posterior reversible encephalopathy syndrome (PRES) Leukomelanosis Leukonychia striata (Mees' lines) Leukoplakia Leukorrhea Libido decreased Libido increased Lichen myxedematosus Lichen nitidus Lichen planopilaris Lichen planus Lichen planus pemphigoides Lichen sclerosus Lichen simplex chronicus Lichen spinulosus Lichen vaccinatus Lichenoid acrodermatitis Lichenoid dermatitis Lichenoid eruption / lichenoid reaction Lichenoid keratoses Lichenoid stomatitis Limbal stem cell deficiency Linear hypopigmentation Linear IgA Linear streaking Lip ulceration Lipoatrophy Lipodermatosclerosis Lipodystrophy Lipogranulomas Lipohypertrophy Lipomatosis Livedo reticularis / livedo racemosa Liver adenomas Lobular panniculitis Longitudinal ridges Loose stools / soft feces Loss of consciousness Low-density lipoprotein (LDL) increased Lower respiratory tract infection Luminous phenomena Lung injury Lupus erythematosus (subacute cutaneous lupus erythematosus (SCLE)) Lupus erythematosus – dermatomyositis Lupus panniculitis Lupus syndrome / drug-induced lupus (DIL) Lupus vulgaris Lymphadenitis Lymphadenopathy Lymphedema Lymphocytic infiltration / Jessner lymphocytic infiltration Lymphocytic thrombophilic arteritis Lymphocytic vasculitis (angiitis) Lymphocytoma cutis Lymphocytosis / lymphocytes increased Lymphoepithelioma Lymphoid hyperplasia Lympholysis Lymphoma Lymphomatoid papulosis Lymphopenia (lymphocytopenia) / lymphocytes decreased Lymphoproliferative disease / lymphoproliferative disorder Macroglossia Macrophage activation syndrome Macular degeneration Macular edema Macular exanthems Macular hole Macular infarction Macular neuroretinopathy Maculopapular rash / morbilliform rash Maculopathy Malaise Malakoplakia Malignancies Malignant hyperthermia Malignant lymphoma Malignant melanoma Malignant neoplasms Mania Mastitis Mastodynia Mean cell volume (MCV) increased / mean corpuscular volume increased Median canaliform dystrophy Meibomian gland dysfunction Meibomianitis Meige's syndrome Melanoma Melanonychia Melanosis / melanocytosis Melanuria Melasma Memory loss/memory impaired Meningococcal infection Meningoencephalitis Meningoradiculitis Menorrhagia Menstrual irregularities Mental status changes Merkel cell carcinoma Mesenteric ischemia / colonic ischemia / intestinal ischemia Metabolic syndrome Methemoglobinemia Metrorrhagia Micturition difficulty Migraine Milia Miliaria Miliaria profunda Minimal change disease (minimal change glomerulopathy) Miosis Miscarriage Molluscum contagiosum Monoclonal gammopathy Monocytosis Mood changes Moon face Morphea / localized scleroderma Movement disorder(s) Mucha-Habermann disease Mucocutaneous eruption Mucocutaneous lymph node syndrome Mucocutaneous reactions Mucocutaneous syndrome Mucosal atrophy Mucosal bleeding Mucosal bullous hemorrhagic dermatosis Mucosal candidiasis Mucosal denudation of lips Mucosal dryness Mucosal inflammation Mucosal irritation Mucosal lesions Mucosal membrane desquamation Mucosal membrane pigmentation Mucosal pigmentation / mucosal discoloration Mucosal ulceration Mucositis Muehrcke's lines Multiorgan failure Multiple sclerosis Multisystem inflammatory syndrome Mural thrombosis Muscle atrophy Muscle spasm Muscle weakness Muscular paralysis Musculoskeletal (non-cardiac) chest pain Musculoskeletal adverse effects Musculoskeletal pain Musculoskeletal stiffness Myalgia Myasthenia gravis Mycosis fungoides Mydriasis Myelitis / myeloradiculitis Myelo-optic-neuropathy Myelodysplastic syndrome Myeloid leukemia Myelopathy Myelosuppression / bone marrow suppression / myelotoxicity Myocardial infarction Myocardial ischemia Myocardial necrosis Myocardial toxicity Myocarditis Myoclonus Myoglobinuria Myokymia / twitching / fasciculation Myopericarditis / perimyocarditis Myopia Myxedema Myxedema coma Nail changes Nail disorder Nail dystrophy Nail growth Nail growth reduced Nail hypoplasia Nail loss Nail pigmentation Nail pitting Nail thickening Nail thinning Nail toxicity Narcolepsy Narcosis Nasal congestion Nasal discomfort Nasal dryness Nasal irritation Nasal polyp Nasal septal perforation Nasopharyngitis Nausea Neck pain Neck rigidity Necrolysis Necrosis (skin necrosis) Necrotizing arteritis Necrotizing enterocolitis Necrotizing fasciitis Necrotizing myelopathy / necrotic myelopathy / subacute necrotic myelopathy Necrotizing myopathy / immune-mediated necrotizing myopathy Necrotizing vasculitis (angiitis) Neoplasms Nephritic syndrome Nephritis / interstitial nephritis / tubulointerstitial nephritis Nephrocalcinosis Nephrogenic diabetes insipidus / arginine vasopressin resistance Nephrogenic systemic fibrosis Nephrolithiasis (kidney stones / renal calculi) Nephropathy Nephrotic syndrome Nephrotoxicity / kidney injury / acute kidney injury (AKI) / drug-induced kidney injury Nerve dysfunction Nervousness Neural tube defects Neuritis Neurodermatitis Neuroleptic malignant syndrome Neurological adverse effect / neurological deficit Neuromyelitis optica Neuromyopathy Neuropathy Neuropsychiatric / neuropsychological adverse effect Neurotoxicity Neutropenia (neutrophils decreased) Neutropenic enterocolitis Neutrophilia / neutrophil leukocytosis / neutrocytosis (neutrophils increased) Neutrophilic dermatosis Neutrophilic eccrine hidradenitis Nevi (naevi) Night blindness Nightmares Nocardiosis Nocturia Nodular eruption Nodular panniculitis Nodular regenerative hyperplasia Nodulocystic lesions Non-cardiogenic pulmonary edema Non-cirrhotic portal hypertension Non-hematological adverse effect Non-Hodgkin's lymphoma Notalgia paresthetica Nummular eczema Nystagmus Ochronosis Ocular adverse effect Ocular allergy Ocular atrophy Ocular burning Ocular cicatricial pemphigoid Ocular deviation Ocular discharge Ocular discomfort Ocular dyskinesia Ocular edema (eye edema) Ocular erythema Ocular flutter Ocular hemorrhage Ocular herpes simplex Ocular hyperemia Ocular hypersensitivity Ocular hypertension Ocular hypotension Ocular icterus Ocular inflammation Ocular injection-site reactions Ocular irritation Ocular ischemia Ocular itching / ocular pruritus Ocular lichenoid eruption Ocular myasthenia gravis Ocular pain Ocular pemphigoid Ocular pigmentation Ocular pressure Ocular sarcoidosis Ocular stinging Ocular surface disorder / ocular surface disease Ocular toxicity Ocular twitching / myokymia Oculo-mucocutaneous syndrome Oculogyric crisis / oculogyric dystonic reaction Oculorespiratory syndrome Odynophagia (painful swallowing) Oily spotting Oligohydramnios (amniotic fluid deficiency) Oligohydrosis (reduced sweating) Oligomenorrhea Oligospermia Oliguria Onychauxis (abnormal nail growth) Onychocryptosis (ingrowing toe nail) Onychodermal band Onychodystrophy Onycholysis Onychomadesis Onychomycosis Onychopathy Onychoschizia Ophthalmitis Ophthalmoplegia Opisthotonus Opsoclonus / opoclonia Opsoclonus-myoclonus-ataxia syndrome Optic atrophy Optic edema Optic neuritis / papillitis Optic neuropathy Oral angioedema Oral bleeding Oral burn Oral candidiasis Oral carcinoma Oral changes Oral edema Oral erythema multiforme Oral lesions Oral lichen planus Oral lichenoid eruption Oral mucosal eruption Oral mucosal erythema Oral mucosal fixed eruption Oral mucosal irritation Oral mucosal lichenoid eruption Oral mucosal paresthesias Oral numbness Oral papillomatosis Oral pemphigus Oral pigmentation Oral psoriasis Oral squamous cell carcinoma Oral ulceration Oral vesiculation Orange-peel skin Orbital (ocular) myositis Orbital cellulitis Orbital inflammation Orbitocranial inflammation Orchitis (inflammation of the testes) Orogenital ulceration Orolingual angioedema Oronasal midline defect Oropharyngeal candidiasis Oropharyngeal discomfort Oropharyngeal edema Oropharyngeal mucositis Oropharyngeal pain Orthostatic hypotension Osteitis Osteoma cutis Osteomalacia Osteomyelitis Osteonecrosis / avascular necrosis Osteopenia Osteoporosis Othello syndrome Otitis (otitis externa, otitis media, otitis interna) Ototoxicity Ovarian cyst Ovarian hyperstimulation syndrome Oxalate nephropathy Pain Pain in extremities Painful eruption of hands Palatal perforation Palinopsia / visual perseveration Pallor Palmar desquamation Palmar erythema Palmar fasciitis Palmar nodules Palmar–plantar desquamation Palmar–plantar erythema Palmar–plantar fixed eruption Palmar–plantar hyperhidrosis Palmar–plantar hyperkeratosis Palmar–plantar pigmentation Palmar–plantar punctate keratoses Palmar–plantar toxicity Palmoplantar lesions Palmoplantar pustulosis Palpitation Pancreatic enzymes increased Pancreatic insufficiency Pancreatitis / acute pancreatitis Pancreatitis, polyarthritis and panniculitis (PPP) syndrome Pancytopenia (includes bicytopenia) Panic attack Panniculitis Papilledema Papillomas Papular elastorrhexis Papular lesions Papulo-nodular lesions Papuloerythroderma Papuloerythroderma of Ofuji Papulopustular eruption Papulovesicular eruption Paralysis / paraplegia Paraneoplastic neurological syndromes Paraneoplastic pemphigus Paranoia Parapsoriasis Paresis Paresthesias Parkinsonism Paronychia Parosmia Parotitis Parrot beak nails Parsonage-Turner syndrome (PTS) (brachial plexopathy; neuralgic amyotrophy) Partial thromboplastin time increased Pavor nocturnus Peeling Pellagra Pelvic pain Pemphigoid nodularis Pemphigus Pemphigus erythematodes (pemphigus erythematosus) (Senear-Usher syndrome) Pemphigus foliaceus Pemphigus herpetiformis Pemphigus vegetans Pemphigus vulgaris Penicillamine-induced degenerative dermopathy Penile disorder Penile edema Penile pain Penile pruritus Penile rash Penile ulceration Peptic ulceration Perceptual disturbance Perforating collagenosis Perforating dermatosis Perforating foot ulceration Perianal candidiasis Perianal fistula Perianal irritation Perianal ulcerations Pericardial effusion Pericarditis Perifolliculitis barbae Perihepatitis Periocular dermatitis Periodontal infection Perioral abscess Perioral dermatitis Perioral paresthesias Periorbital dermatitis Periorbital edema Periorbital hematoma Periorbital pigmentation Periorbital rash Periorbital urticaria Periorbitopathy / periorbital syndrome Periostitis / periostitis deformans Peripheral edema Peripheral ischemia Peripheral neuropathy Peripheral vasculopathy Peristalsis increased Peritonitis Periungal hyperpigmentation Periungual granuloma Periungual infection Periungual inflammation Periventricular leukomalacia Perleche Pernio / chilblain Perniosis Petechiae Peyronie's disease Pharyngitis (sore throat) Pharyngolaryngeal pain Phlebitis Photo-onycholysis Photoaging / dermatoheliosis Photoallergic reaction Photocontact dermatitis Photophobia Photopigmentation Photopsia Photosensitivity Phototoxic bullous eruption Phototoxicity Phytophotodermatitis / berloque dermatitis Pigmentation Pigmented purpuric dermatosis / eruption Pigskin appearance Pili torti Piloerection Pincer nails Pink urine syndrome Pisa syndrome (pleurothotonus) Pituitary apoplexy Pityriasis amiantacea Pityriasis lichenoides / pityriasis lichenoides chronica / pityriasis lichenoides et varioliformis acuta Pityriasis rosea Pityriasis rubra pilaris Pityriasis versicolor Plantar fasciitis Plasmacytosis Platelet function defects Pleural effusion Pleuritic pain Pleuropericarditis Pneumatosis intestinalis / pneumatosis cystoides intestinalis Pneumocystis jirovecii pneumonia Pneumonia Pneumonitis Pneumoperitoneum Pneumothorax Podocytopathy Poikiloderma Poliosis Pollakiuria Polyarteritis nodosa Polychondritis Polycythemia / erythrocytosis Polyfibromatosis Polymyalgia rheumatica Polymyositis Polyuria (includes polyuric syndrome) Pompholyx / dyshidrotic eczema Porokeratosis Porphyria Porphyria cutanea tarda Porphyria variegata Port-wine stain Posterior capsule opacification Posterior subcapsular cataracts Postural hypotension PQ (PR) interval prolonged Preeclampsia Pregnancy outcomes Premature atrial contractions Premature ventricular contractions Pressure necrosis Presyncope Preterm birth/labor Priapism Primary central nervous system lymphoma (PCNSL) Procalcitonin (PCT) increased Proctalgia fugax (rectal pain) Proctitis Proptosis Prostate cancer Prostatism Prostatitis Proteinuria Prothrombin time (INR) increased Prothrombin time decreased Proximal femoral focal deficiency Prurigo Prurigo nodularis Prurigo pigmentosa Pruritic rash Pruritus (itching) Pruritus ani et vulvae Pseudo-mongolian spot Pseudoacanthosis nigricans Pseudofolliculitis barbae Pseudohallucinations Pseudolithiasis / biliary pseudolithiasis Pseudolymphoma / cutaneous pseudolymphoma Pseudomelanosis ilei Pseudomembranous colitis Pseudomenopause Pseudoparkinsonism Pseudopolymyalgia Pseudoporphyria Pseudoporphyria cutanea tarda Pseudoscleroderma Pseudotumor cerebri Pseudoxanthoma elasticum Psoriasiform dermatitis Psoriasiform eruption Psoriasis Psoriasis (nails) Psoriatic arthralgia / psoriatic arthritis Psychiatric adverse effect Psychomotor hyperactivity Psychomotor impairment Psychosis Pulmonary adverse effect Pulmonary edema / cardiogenic pulmonary edema Pulmonary embolism Pulmonary fibrosis Pulmonary function test decreased Pulmonary granuloma Pulmonary hemorrhage Pulmonary hypertension Pulmonary infection Pulmonary infiltrate Pulmonary Infiltration with Eosinophilia (PIE) syndrome Pulmonary lymphadenopathy Pulmonary sarcoidosis Pulmonary toxicity Pulmonary-renal syndrome Punctate keratitis Punding Pure red cell aplasia Pure white cell aplasia Purple glove syndrome Purple gloves and socks syndrome Purplish erythema Purpura Purpura fulminans Pustules / pustular eruption Pustuloderma Pyelonephritis Pyloric stenosis Pyoderma Pyoderma gangrenosum Pyogenic granuloma Pyrosis (heartburn) Pyuria QT interval prolonged / QT prolongation QT interval shortening Rabbit syndrome Radiation adverse effect Radiation keratosis Radiation recall dermatitis Radiation recall pneumonitis Radiation skin injury Rash Raynaud's phenomenon Recall reaction Rectal burning Rectal hemorrhage / rectal bleeding Rectal itch Rectal mucosal ulceration Rectal perforation Rectitis Rectus sheath hematoma Red man syndrome Red neck syndrome Red stools / hematochezia Reduced visual acuity Reiter's syndrome (reactive arthritis) Remitting seronegative symmetrical synovitis with pitting edema syndrome Renal disorder Renal failure Renal function abnormal / renal dysfunction Renal insufficiency Renal phospholipidosis Renal tubular acidosis Renal tubular necrosis Residual urine volume increased / post-void residual (PVR) urine Respiratory depression Respiratory disorder Respiratory distress Respiratory dyskinesia Respiratory failure Respiratory tract infection Restless legs syndrome / Willis-Ekbom disease (includes restless arms syndrome variant) Restlessness Retching Reticular hyperplasia Retinal adverse effect Retinal angiomatous proliferation Retinal artery occlusion Retinal atrophy Retinal detachment Retinal disorder Retinal edema Retinal pigment epithelial detachment (RPED) Retinal pigmentation Retinal vasculitis Retinal vein occlusion Retinitis Retinopathy Retrobulbar hematoma Retrograde ejaculation Retroperitoneal bleeding Retroperitoneal fibrosis (Ormond's disease) Reversible cerebral vasoconstriction syndrome (RCVS) Rhabdomyolysis Rheumatoid arthritis Rheumatoid nodules Rhinitis / rhinosinusitis (see also sinusitis) Rhinoconjunctivitis Rhinophyma Rhinorrhea Rhinorrhoea Rhonchi Ridging Rigors Rosacea Rosacea fulminans Rowell syndrome / Rowell’s syndrome Sacroiliitis Salivary gland enlargement Salivary hypersecretion Salpingitis (inflammation of the fallopian tubes) Salt-wasting syndrome Sarcoidosis / sarcoid-like reaction (cutaneous sarcoidosis) Sarcoma Sarcopenia Scabbing Scabies Scaling Scalp burning Scalp defects Scalp dermatitis Scalp tingling Scar Schamberg's disease Schizophrenia Scleral pigmentation Scleredema Scleritis Sclerodactyly Scleroderma Sclerosing lipogranuloma Sclerosis Sclerotic plaques Scoliosis Scotoma Scrofuloderma Scrotal edema Scrotal gangrene / Fournier's gangrene Scrotal ulceration SDRIFE Sebaceous hyperplasia Seborrhea Seborrheic dermatitis Seborrheic keratoses Sedation Seizures Sensitivity Sensitization Sensory disturbances Sepsis Septic–toxic shock Serositis / polyserositis Serotonin syndrome Serous retinopathy Serpentine tongue Serum creatinine increased Serum myoglobin increased Serum sickness Serum sickness-like reaction Serum tumor marker increased Sexual dysfunction Sexual fantasies Sézary syndrome Shield ulcer Shivering Shock Shoreline nails Sialadenitis Sialolithiasis Sialopenia Sialorrhea (ptyalism; hypersalivation) Side effects Sideroblastic anemia Sinonasal disease Sinus node dysfunction (sick sinus syndrome) Sinus tachycardia Sinusitis (see also rhinitis / rhinosinusitis) Sinusoidal obstruction syndrome Sjögren’s syndrome (see also sicca syndrome) Skeletal fluorosis Skeletal toxicity Skin (dermatological) reaction Skin cancer Skin fragility Skin infection Sleep apnea Sleep disturbances Sleep-related disorder Sleep-related eating disorder (SRED) Slurred speech Sneezing (sternutation) Snoring Somnambulism (sleepwalking; noctambulism) Somnolence Speech disorder Spider angioma Spider nevi Spinal cord compression Spinal cord infarction Spinal epidural hematoma Splenomegaly Splinter hemorrhage Spontaneous ejaculation Squamous cell carcinoma Squamous cell carcinoma in situ (Bowen disease) Squamous syringometaplasia Staphylococcal scalded skin syndrome Status epilepticus Status gelasticus Steatorrhea (fatty stool) Stevens-Johnson syndrome Stickiness Stiff person syndrome Still's disease Stinging Stomatitis (oral mucositis) Stomatodynia Strabismus (squint) Straight hair Striae Stridor Stroke / cerebrovascular accident Stupor Stuttering (dysphemia) / stammering Subacute thrombosis Subarachnoid hemorrhage Subconjunctival hemorrhage Subcorneal pustular dermatosis (Sneddon-Wilkinson disease) Subcutaneous fat necrosis Subdural hemorrhage Subungual abscess Subungual hematoma / subungual hemorrhage Subungual hyperkeratosis Suicidal ideation Sulfhemoglobinemia Sunburn Supraventricular arrhythmias Supraventricular tachycardia Susac's syndrome / retino-cochleo-cerebral vasculopathy Sweat gland necrosis Sweet syndrome Symblepharon Syncope / fainting Synovial effusions Systemic inflammatory response syndrome (SIRS) Systemic reactions Systemic sclerosis Systolic dysfunction / ejection fraction reduced Tachyarrhythmia Tachycardia Tachypnea / respiratory rate increased Takotsubo syndrome Tardive seizure Tardive syndrome / tardive dyskinesia Tardive syndrome / tardive dystonia (includes oromandibular dystonia) Teardrop sign Telangiectasia Tenderness Tendinitis Tendinopathy Tendinous contracture Tendon xanthomata Tenesmus Teratogenicity Testicular atrophy Testicular hydrocele Testicular pain / orchialgia / orchidalgia Tetanic contractions Thickening Thinning Throat irritation Thrombocythemia (thrombocytosis) / platelets increased Thrombocytopenia / platelets decreased Thrombocytopenic purpura Thromboembolism Thrombophlebitis Thrombosis Thrombotic complications Thrombotic microangiopathy Thrombotic thrombocytopenic purpura Thrombus Thyroid disorder Thyroid dysfunction Thyroiditis Thyrotoxic periodic paralysis Thyrotoxicosis Tic disorder Tinea Tinnitus Tongue disorder Tongue edema Tongue erosions Tongue fungiform papillae hypertrophy Tongue furry Tongue geographic Tongue hematoma / lingual hematoma Tongue hemorrhage Tongue irritation Tongue lesions Tongue necrosis Tongue numb Tongue pigmentation Tongue ulceration Tonsillitis Tooth decay Tooth disorder Tooth fluorosis Tooth pigmentation / discoloration Toothache (odontalgia) Torsades de pointes Torticollis Tourette's syndrome Toxic dermatitis Toxic erythema Toxic pustuloderma Toxic-allergic shock Toxicoderma Toxoplasmosis Tracheobronchial secretions / bronchial secretions Transient acantholytic dermatosis (Grover's disease) Transient vision loss (amaurosis fugax) Transverse depression Transverse superficial loss of nail plate Trembling Tremor Trichomegaly Trichoptilosis Trichotillomania (hair-pulling disorder) Trismus Tuberculosis Tuberculous arthritis Tumor lysis syndrome (TLS) Tumor pain Tumors Turbinate hyperplasia Ulceration of psoriatic plaques Ulcerations Ulcerative colitis Ulcerative esophagitis Ulcerative necrosis Ulcerative stomatitis Ultraviolet light recall Upper airway obstruction Upper respiratory tract infection Upper respiratory tract inflammation Uremia Urethral burning Urethritis Uric aciduria Urinary casts Urinary disorder Urinary frequency Urinary hesitancy Urinary obstruction Urinary retention Urinary tract infection Urogenital tuberculosis Urogenital ulceration Urolithiasis / ureteral stones Uropathy Urosepsis Urticaria / hives Urticaria pigmentosa Uterine bleeding Uterine hyperstimulation Uterine pain Uterine rupture Uterine spasm Uveitis / anterior uveitis / posterior uveitis / panuveitis Vaccine-induced immune thrombotic thrombocytopenia / vaccine-induced thrombotic thrombocytopenia Vaccinia Vaccinia gangrenosum Vaccinia necrosum Vaginal bleeding Vaginal discharge Vaginal dryness Vaginal pruritus Vaginal ulceration Vaginitis Valve regurgitation Valvulopathy Vanishing bile duct syndrome / ductopenia Varicella zoster Varicosities Vascular leak syndrome Vascular occlusion Vascular trauma Vasculitis (angiitis) / cutaneous vasculitis (angiitis) Vasoconstriction Vasodilation Vasospasm Veno-occlusive disease Venous thromboembolism Ventricular arrhythmia Ventricular dysfunction (left ventricular dysfunction / right ventricular dysfunction) Ventricular ectopy (ventricular ectopics) / premature ventricular contraction (PVC) Ventricular fibrillation Ventricular hypertrophy Ventricular tachycardia Verrucae vulgaris / warts / verrucae Verrucous lesions Vertigo Vesiculation Vesiculobullous eruption Vestibular disorder / vestibulopathy Virilization Viscerotropic disease (multiple organ system dysfunction) Vision blurred Vision disorders Vision impaired Vision loss Visual disturbances Visual halos Vitamin B-12 deficiency Vitelliform maculopathy / acquired vitelliform maculopathy / vitelliform macular dystrophy Vitiligo Vitreous detachment Vitreous floaters / floaters / myodesopsia / myiodesopsia / muscae volitantes Vitreous hemorrhage Vocal cord palsy Vocal fold hemorrhage Vogt-Koyanagi-Harada syndrome Vomiting Vulvar ulceration Vulvovaginal burning Vulvovaginal candidiasis Vulvovaginal pruritus Vulvovaginalmycotic infection Warm feeling (includes feeling hot) Weight gain Weight loss Wheezing White dot syndrome Worsening renal function Wound complications Wrinkling Xanthoderma Xanthomas Xerophthalmia (dry eyes) Xerosis / xeroderma Xerostomia (dry mouth) Yawning Yellow palms