Captopril

Breastfeeding Pediatric
  • TRADE NAME: Acenorm; Acepril; Adocor; APO-Capto; Capoten (Par); Capozide (Par); Captolane; Captoril; Lopirin; Lopril; Nu-Capto; Precaptil
  • INDICATIONS: Hypertension; congestive heart failure; to improve survival following myocardial infarction in clinically stable patients with left ventricular dysfunction; diabetic nephropathy in patients with Type I insulin-dependent diabetes mellitus and retinopathy
  • CLASS: Angiotensin-converting enzyme (ACE) inhibitor, Antihypertensive, Vasodilator
  • HALF-LIFE: <3 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Alcohol, Aldesleukin, Allopurinol, Alpha blockers, Alprostadil, Amifostine, Amiloride, Angiotensin II receptor antagonists, Antacids, Antidiabetics, Antihypertensives, Antipsychotics, Anxiolytics and hypnotics, Aprotinin, Azathioprine, Baclofen, Beta blockers, Calcium channel blockers, Clonidine, Cyclosporine, CYP2D6 inhibitors, Darunavir, Diazoxide, Digoxin, Diuretics, Eplerenone, Estrogens, Everolimus, General anesthetics, Gold and Gold Compounds, Heparins, Herbals, Hydralazine, Hypotensives, Insulin, Interferon Alfa, Levodopa, Lithium, MAO inhibitors, Metformin, Methyldopa, Methylphenidate, Minoxidil, Moxisylyte, Moxonidine, Nitrates, Nitroprusside, NSAIDs, Pentoxifylline, Phosphodiesterase 5 inhibitors, Potassium salts, Probenecid, Prostacyclin analogues, Rituximab, Salicylates, Sirolimus, Spironolactone, Sulfonylureas, Temsirolimus, Tizanidine, Tolvaptan, Triamterene, Trimethoprim, Yohimbine

PREGNANCY CATEGORY: D

category C in first trimester; category D in second and third trimesters

Capozide is captopril and hydrochlorothiazide.

Our database has 124 adverse reactions for this drug across the following areas

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SKIN
HAIR
NAILS
MUCOSAL
CARDIOVASCULAR
CENTRAL NERVOUS SYSTEM
NEUROMUSCULAR/SKELETAL
GASTROINTESTINAL/HEPATIC
RESPIRATORY
ENDOCRINE/METABOLIC
GENITOURINARY
RENAL
HEMATOLOGIC
OCULAR
OTHER
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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life Threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric