Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Disoproxil

BreastfeedingGeriatricPediatric

FDA APPROVAL DATE: 08/27/2012

CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Acyclovir, Adefovir, Amiodarone, Amitriptyline, Amlodipine, Antacids, Antirarrhythmics, Antiretrovirals, Atorvastatin, Benzodiazepines, Bepridil, Beta blockers, Bosentan, Buprenorphine, Bupropion, Buspirone, Calcium channel blockers, Carbamazepine, Cidofovir, Clarithromycin, Clonazepam, Clorazepate, Colchicine, Cyclosporine, Desipramine, Dexamethasone, Diazepam, Digoxin, Diltiazem, Disopyramide, Drugs affecting renal function, Elbasvir & Grazoprevir, Emtricitabine, Estazolam, Ethosuximide, Felodipine, Flecainide, Flurazepam, Fluticasone Propionate, Ganciclovir, Hormonal contraceptives, Imipramine, Immunosuppressants, Itraconazole, Ketoconazole, Lamivudine, Ledipasvir & Sofosbuvir, Lidocaine, Metoprolol, Mexiletine, Midazolam, Naloxone, Neuroleptics, Nicardipine, Nifedipine, Non-nucleoside reverse transcriptase inhibitors, Nortriptyline, Oxcarbazepine, Paroxetine Hydrochloride, Perphenazine, Phenobarbital, Phenytoin, Propafenone, Protease inhibitors, Quinidine, Rifabutin, Rifapentine, Risperidone, Ritonavir, Salmeterol, Sedatives / hypnotics, Sildenafil, Simeprevir, Sirolimus, SSRIs, Tacrolimus, Tadalafil, Telithromycin, Tenofovir Disoproxil, Thioridazine, Timolol, Trazodone, Tricyclic antidepressants, Valacyclovir, Valganciclovir, Vardenafil, Verapamil, Voriconazole, Warfarin, Zolpidem

PREGNANCY CATEGORY: B

See also separate profiles for emtricitabine and tenofovir disoproxil.

LACTIC ACIDOSIS/SEVERE HEPATOMEGALY WITH STEATOSIS and POST TREATMENT ACUTE EXACERBATION OF HEPATITIS B

See full prescribing information for complete boxed warning.

Our database has 33 adverse reactions for this drug across the following areas

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SKIN
CARDIOVASCULAR
CENTRAL NERVOUS SYSTEM
NEUROMUSCULAR/SKELETAL
GASTROINTESTINAL/HEPATIC
RESPIRATORY
ENDOCRINE/METABOLIC
GENITOURINARY
RENAL
OCULAR
OTHER


Page last updated 09/19/2018

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric