Cyclosporine

BreastfeedingPediatric
  • TRADE NAMES: Ciclosporin; Consupren; Implanta; Neoral (Novartis); Restasis (Allergan); Sandimmun; Sandimmune (Novartis)
  • INDICATIONS: Rheumatoid arthritis, prophylaxis of organ rejection in transplants, psoriasis; Restasis is indicated for patients with moderate-to-severe dry eye syndrome
  • SYNONYM: CsA; CyA
  • CLASS: Calcineurin inhibitor, Disease-modifying antirheumatic drug (DMARD), Immunosuppressant
  • HALF-LIFE: 10–27 hours (adults)
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Afatinib, Aliskiren, Ambrisentan, Amiloride, Aminoglycosides, Amiodarone, Amphotericin B, Ampicillin, Amprenavir, Anisindione, Anticoagulants, Armodafinil, Atazanavir, Atorvastatin, Azathioprine, Azithromycin, Bacampicillin, Basiliximab, Benazepril, Bezafibrate, Boceprevir, Bosentan, Bupropion, Captopril, Carbenicillin, Caspofungin, Ceritinib, Cholestyramine, Cholic Acid, Choline Fenofibrate, Cilazapril, Ciprofloxacin, Clarithromycin, Cloxacillin, Co-Trimoxazole, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Disoproxil, Colchicine, Colesevelam, Corticosteroids, Cyclophosphamide, Dabigatran, Daclizumab, Danazol, Daptomycin, Darifenacin, Darunavir, Dasatinib, Delavirdine, Dichlorphenamide, Diclofenac, Dicloxacillin, Dicumarol, Digoxin, Diltiazem, Disulfiram, Docetaxel, Doxycycline, Dronedarone, Echinacea, Efavirenz, Elbasvir & Grazoprevir, Eluxadoline, Enalapril, Enasidenib, Enzalutamide, Erythromycin, Ethotoin, Etoposide, Etoricoxib, Everolimus, Ezetimibe, Flunisolide, Fluoxymesterone, Fluvastatin, Foscarnet, Fosinopril, Fosphenytoin, Gemfibrozil, Glecaprevir & Pibrentasvir, Grapefruit Juice, Hemophilus B Vaccine, HMG-CoA reductase inhibitors, Imatinib, Imipenem/Cilastatin, Indinavir, Influenza Vaccine, Irbesartan, Itraconazole, Ketoconazole, Lanreotide, Letermovir, Levofloxacin, Lisinopril, Lopinavir, Lovastatin, Meloxicam, Mephenytoin, Methicillin, Methoxsalen, Methylphenidate, Methylprednisolone, Methyltestosterone, Mezlocillin, Micafungin, Mifepristone, Mizolastine, Moxifloxacin, Mycophenolate, Nafcillin, Naldemedine, Natalizumab, Nelfinavir, Neratinib, Nevirapine, Nifedipine, Nisoldipine, Norfloxacin, NSAIDs, Ofloxacin, Olmesartan, Omeprazole, Orlistat, Osimertinib, Oxacillin, Oxcarbazepine, Pasireotide, Penicillins, Phenytoin, Pitavastatin, Posaconazole, Pravastatin, Prednisolone, Prednisone, Pristinamycin, Quinapril, Rabeprazole, Ramipril, Ranolazine, Ribociclib, Rifabutin, Rifampin, Rifapentine, Ritonavir, Rosuvastatin, Sevelamer, Silodosin, Simvastatin, Sirolimus, Sofosbuvir/Velpatasvir/Voxilaprevir, Spironolactone, St John's Wort, Sulfacetamide, Sulfadiazine, Sulfamethoxazole, Sulfisoxazole, Sulfonamides, Tacrolimus, Telithromycin, Temsirolimus, Tenoxicam, Terbinafine, Testosterone, Ticarcillin, Tinidazole, Tipranavir, Tofacitinib, Tolvaptan, Trabectedin, Trandolapril, Triamterene, Trimethoprim, Troleandomycin, Ursodiol, Vaccines, Vecuronium, Venetoclax, Voriconazole, Warfarin, Zofenopril

PREGNANCY CATEGORY: C

Restasis is an ophthalmic emulsion.

Our database has 199 adverse reactions for this drug across the following areas

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SKIN
HAIR
NAILS
MUCOSAL
CARDIOVASCULAR
CENTRAL NERVOUS SYSTEM
ENDOCRINE/METABOLIC
GASTROINTESTINAL/HEPATIC
GENITOURINARY
HEMATOLOGIC
NEUROMUSCULAR/SKELETAL
OCULAR
OTIC
RENAL
RESPIRATORY
OTHER


Page last updated 04/23/2019

Drug Eruption Mobile Site

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric