Pimavanserin

BreastfeedingGeriatricPediatric
  • TRADE NAME: Nuplazid (Acadia)
  • INDICATIONS: Hallucinations and delusions associated with Parkinson’s disease psychosis
  • CLASS: Antipsychotic
  • HALF-LIFE: 57 hours

FDA APPROVAL DATE: 04/29/2016

CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Amiodarone, Carbamazepine, Chlorpromazine, Clarithromycin, Disopyramide, Drugs known to prolong the QT interval, Gatifloxacin, Indinavir, Itraconazole, Ketoconazole, Moxifloxacin, Phenytoin, Procainamide, Quinidine, Rifampin, Sotalol, St John's Wort, Strong CYP3A4 inhibitors and inducers, Thioridazine, Ziprasidone

PREGNANCY CATEGORY: N/A
No available data to inform drug-associated risk

INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS

See full prescribing information for complete boxed warning

Our database has 18 adverse reactions for this drug across the following areas

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SKIN
CARDIOVASCULAR
CENTRAL NERVOUS SYSTEM
GASTROINTESTINAL/HEPATIC
GENITOURINARY
HEMATOLOGIC
OTHER


Page last updated 09/19/2018

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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