Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Alafenamide

Breastfeeding

FDA APPROVAL DATE: 11/05/2015 (Genvoya)

CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Acyclovir, Aminoglycosides, Amiodarone, Amitriptyline, Amlodipine, Antacids, Antiarrhythmics, Atorvastatin, Benzodiazepines, Bepridil, Beta blockers, Bosentan, Buprenorphine, Bupropion, Buspirone, Calcium channel blockers, Cidofovir, Clarithromycin, Clorazepate, Colchicine, Desipramine, Dexamethasone, Diazepam, Digoxin, Diltiazem, Disopyramide, Drugs affecting renal function, Estazolam, Ethosuximide, Felodipine, Flecainide, Flurazepam, Fluticasone Furoate, Fluticasone Propionate, Ganciclovir, Gentamicin, Hormonal contraceptives, Imipramine, Immunosuppressants, Itraconazole, Ketoconazole, Lidocaine, Lorazepam, Metoprolol, Mexiletine, Midazolam, Naloxone, Neuroleptics, Nicardipine, Nifedipine, Nortriptyline, Oxcarbazepine, Paroxetine Hydrochloride, Perphenazine, Propafenone, Quinidine, Rifabutin, Rifapentine, Risperidone, Salmeterol, Sildenafil, SSRIs, Tadalafil, Telithromycin, Thioridazine, Timolol, Trazodone, Tricyclic antidepressants, Valacyclovir, Valganciclovir, Vardenafil, Verapamil, Voriconazole, Warfarin, Zolpidem

PREGNANCY CATEGORY: B

See also separate profiles for emtricitabine and tenofovir alafenamide.

LACTIC ACIDOSIS/SEVERE HEPATOMEGALY WITH STEATOSIS and POST TREATMENT ACUTE EXACERBATION OF HEPATITIS B

See full prescribing information for complete boxed warning.

Our database has 9 adverse reactions for this drug across the following areas

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CENTRAL NERVOUS SYSTEM
NEUROMUSCULAR/SKELETAL
GASTROINTESTINAL/HEPATIC
RESPIRATORY
OCULAR
OTHER


Page last updated 08/08/2017

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric