Risperidone

Breastfeeding Pediatric
  • TRADE NAME: Risperdal (Ortho-McNeil, Janssen); Risperdal Consta (Ortho-McNeil, Janssen)
  • INDICATIONS: Schizophrenia, bipolar mania, irritability associated with autistic disorder
  • CLASS: Antipsychotic, Mood stabilizer
  • HALF-LIFE: 3–30 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

ACE inhibitors, Alcohol, Alpha blockers, Amantadine, Anesthetics, general, Angiotensin II receptor antagonists, Anxiolytics and hypnotics, Apomorphine, Artemether/Lumefantrine, Barbiturates, Bromocriptine, Cabergoline, Calcium channel blockers, Carbamazepine, Cimetidine, Citalopram, Clozapine, Ethosuximide, Fluoxetine, Histamine, Levodopa, Levodopa, Memantine, Methyldopa, Metoclopramide, Opioid analgesics, Oxcarbazepine, Paliperidone, Paroxetine, Pergolide, Phenytoin, Pramipexole, Primidone, Ranitidine, Ritonavir, Ropinirole, Rotigotine, Sodium Oxybate, Sympathomimetics, Tetrabenazine, Tramadol, Tricyclics, Valproic Acid

PREGNANCY CATEGORY: C

Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Risperidone is not approved for the treatment of patients with dementia-related psychosis.

[C] = Children; [A] = Adults.

Safety and effectiveness have not been established for pediatric patients with schizophrenia <13 years of age, for bipolar mania <10 years of age, and for autistic disorder <5 years of age.

Our database has 218 adverse reactions for this drug across the following areas

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SKIN
HAIR
NAILS
MUCOSAL
CARDIOVASCULAR
CENTRAL NERVOUS SYSTEM
NEUROMUSCULAR/SKELETAL
GASTROINTESTINAL/HEPATIC
RESPIRATORY
ENDOCRINE/METABOLIC
GENITOURINARY
RENAL
HEMATOLOGIC
OTIC
OCULAR
LOCAL
OTHER
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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life Threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric