Propoxyphene

  • TRADE NAME: Algafan; Antalvic; Darvocet-N (Xanodyne); Darvon (Xanodyne); Darvon Compound (Xanodyne); Develin; Dolotard; Doloxene; Liberan; Parvon
  • INDICATIONS: Pain
  • CLASS: Opiate agonist
  • HALF-LIFE: 8–24 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Alcohol, Alprazolam, Amitriptyline, Carbamazepine, Insulin Aspart, Insulin Glargine, Linezolid, Lisdexamfetamine , Metoprolol, Phenelzine, Ritonavir, Warfarin

PREGNANCY CATEGORY: C

category D with prolonged use

NOTE

Darvocet is propoxyphene and acetaminophen; Darvon Compound is propoxyphene and aspirin.

This drug has been withdrawn from the European Market. Xanodyne has voluntarily removed its products from the US market. The FDA is advising healthcare professionals to stop prescribing propoxyphene to their patients.

Our database has 22 adverse reactions for this drug across the following areas

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SKIN
MUCOSAL
CARDIOVASCULAR
CENTRAL NERVOUS SYSTEM
OCULAR
LOCAL
OTHER
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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life Threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric