Piperacillin

  • TRADE NAME: Avocin; Ivacin; Picillin; Pipcil; Piperilline; Pipracil (Wyeth); Pipril; Piprilin; Pitamycin; Zosyn (Wyeth)
  • INDICATIONS: Various infections caused by susceptible organisms
  • CLASS: Antibiotic, penicillin
  • HALF-LIFE: 0.6–1.2 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Anisindione, Anticoagulants, Atracurium, Cisatracurium, Demeclocycline, Dicumarol, Doxacurium, Doxycycline, Imipenem/Cilastatin, Methotrexate, Minocycline, Non-depolarizing muscle relaxants, Oxytetracycline, Pancuronium, Rapacuronium, Reteplase, Tetracycline, Warfarin

PREGNANCY CATEGORY: B

NOTE

Zosyn is piperacillin and tazobactam - see additional profile for the combination Piperacillin/Tazobactam for further information.

Our database has 53 adverse reactions for this drug across the following areas

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SKIN
MUCOSAL
CARDIOVASCULAR
CENTRAL NERVOUS SYSTEM
NEUROMUSCULAR/SKELETAL
GASTROINTESTINAL/HEPATIC
GENITOURINARY
RENAL
HEMATOLOGIC
OTIC
LOCAL
OTHER
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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life Threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric