Abstract
Fanconi syndrome is a rare adverse effect of tenofovir disoproxil fumarate (TDF). Tenofovir alafenamide fumarate (TAF) is a novel prodrug with less nephrotoxicity. We report resolution of Fanconi syndrome in a HIV and hepatitis B coinfected patient switched from TDF to TAF.
Keywords:
Fanconi syndrome; HIV; hepatitis B; tenofovir alafenamide.
MeSH terms
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Adenine / administration & dosage
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Adenine / analogs & derivatives*
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Alanine
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Anti-HIV Agents / administration & dosage*
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Anti-HIV Agents / adverse effects*
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Coinfection / complications
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Coinfection / drug therapy
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Fanconi Syndrome / chemically induced*
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HIV Infections / complications*
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HIV Infections / drug therapy
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Hepatitis B, Chronic / complications*
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Humans
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Male
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Middle Aged
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Tenofovir / administration & dosage
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Tenofovir / adverse effects*
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Treatment Outcome
Substances
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Anti-HIV Agents
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Tenofovir
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tenofovir alafenamide
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Adenine
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Alanine