Imatinib-Induced Tremor in a Patient with Chronic Myeloid Leukemia in Chronic Phase

Khaldun Obeidat; Arwa Alsaud; Amr Ashour; Bahjat Azrieh; Mohammad Abu-Tineh; Shehab Fareed Mohamed; Mohamed A Yassin

doi:10.1159/000504937

Imatinib-Induced Tremor in a Patient with Chronic Myeloid Leukemia in Chronic Phase

Case Rep Oncol. 2019 Dec 9;12(3):913-917. doi: 10.1159/000504937. eCollection 2019 Sep-Dec.

Authors

Khaldun Obeidat^{1

1

1}, Arwa Alsaud^{1

1

1}, Amr Ashour^{1

1

1}, Bahjat Azrieh^{1

1

1}, Mohammad Abu-Tineh^{1

1

1}, Shehab Fareed Mohamed^{2

2

2}, Mohamed A Yassin^{2

2

2}

Affiliations

¹ Department of Medical Education, Hamad Medical Corporation, Doha, Qatar.
² Department of Medical Education, Hamad Medical Corporation, Department of Medical Oncology, NCCCR, Hamad Medical Corporation, Doha, Qatar.

Abstract

Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by three phases: chronic, accelerated, and blast phase. However; first- and second-generation tyrosine kinase inhibitors are used for the treatment of CML with common and uncommon adverse events. Here, we report a 24-year-old male with CML in chronic phase started on imatinib as upfront medication who developed tremor and recovered spontenously after 3 years.

Keywords: Chronic myeloid leukemia; Imatinib; Side effects; Tremor; Tyrosine kinases.

Publication types

Case Reports