Severe hypofibrinogenemia associated with imatinib and prednisone therapy in Philadelphia chromosome-positive acute lymphoblastic leukemia

Leuk Lymphoma. 2018 Oct;59(10):2516-2517. doi: 10.1080/10428194.2018.1429603. Epub 2018 Jan 31.

Authors

Mariarita Sciumè¹, Nicola Stefano Fracchiolla¹, Agostino Cortelezzi¹

Affiliation

¹ a Hematology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan , Milan , Italy.

PMID: 29384412
DOI: 10.1080/10428194.2018.1429603

No abstract available

MeSH terms

Adult
Afibrinogenemia / blood
Afibrinogenemia / chemically induced
Afibrinogenemia / diagnosis
Afibrinogenemia / epidemiology*
Aged
Antineoplastic Combined Chemotherapy Protocols / adverse effects*
Female
Fibrinogen / analysis
Humans
Imatinib Mesylate / adverse effects*
Incidence
Male
Middle Aged
Philadelphia Chromosome
Precursor Cell Lymphoblastic Leukemia-Lymphoma / blood
Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
Prednisone / adverse effects*
Retrospective Studies
Severity of Illness Index
Treatment Outcome
Young Adult

Substances

Imatinib Mesylate
Fibrinogen
Prednisone