Abstract
A tyrosine kinase inhibitor (STI571, Gleevec) has recently been applied in the treatment of chronic myeloid leukemia. We present the first reported case of pityriasis rosea occurring as a reaction to Gleevec in a woman with blast crisis of this disorder. It is suggested that although coincidental, this exanthem may be due to this agent.
Copyright 2002 S. Karger AG, Basel
MeSH terms
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Adult
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Antineoplastic Agents / adverse effects*
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Benzamides
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Drug Eruptions / etiology*
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Female
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Humans
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Imatinib Mesylate
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Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy
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Piperazines / adverse effects*
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Pityriasis Rosea / chemically induced*
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Pyrimidines / adverse effects*
Substances
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Antineoplastic Agents
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Benzamides
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Piperazines
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Pyrimidines
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Imatinib Mesylate