Thalidomide-induced organizing pneumonia

South Med J. 2006 Nov;99(11):1292-4. doi: 10.1097/01.smj.0000233182.06540.00.

Abstract

Twenty medications are associated with drug-induced organizing pneumonia; however, thalidomide is not listed as a potential causative agent. Thalidomide (Thalomid, Celgene Corp., Summit, NJ), an angiogenesis inhibitor and immunomodulator that reduces tumor necrosis factor-alpha, is used for the treatment of multiple myeloma. We report a case of organizing pneumonia in a 58-year-old male with multiple myeloma treated with dexamethasone and thalidomide.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Angiogenesis Inhibitors / adverse effects*
  • Angiogenesis Inhibitors / therapeutic use
  • Cryptogenic Organizing Pneumonia / chemically induced*
  • Cryptogenic Organizing Pneumonia / diagnostic imaging
  • Cryptogenic Organizing Pneumonia / pathology
  • Humans
  • Immunosuppressive Agents / adverse effects*
  • Immunosuppressive Agents / therapeutic use
  • Male
  • Multiple Myeloma / drug therapy
  • Thalidomide / adverse effects*
  • Thalidomide / therapeutic use
  • Tomography, X-Ray Computed

Substances

  • Angiogenesis Inhibitors
  • Immunosuppressive Agents
  • Thalidomide