The relationship between acute coronary syndrome and sildenafil

Am J Emerg Med. 2013 Sep;31(9):1424.e1-3. doi: 10.1016/j.ajem.2013.05.019. Epub 2013 Jun 19.

Abstract

Sildenafil is a drug used for male erectile dysfunction. Sildenafil's fatal cardiac effects except due to hypotension with simultaneous nitrate use have not been reported.We reported in this case a 70-year-old man admitted to the emergency service with chest pain, which occurs in an hour after sildenafil use. Electrocardiogram showed inferoposterior ST-segment elevation. In angiography, total circumflex artery occlusion has been seen.

Publication types

  • Case Reports

MeSH terms

  • Acute Coronary Syndrome / chemically induced*
  • Acute Coronary Syndrome / physiopathology
  • Aged
  • Chest Pain / chemically induced
  • Coronary Angiography
  • Electrocardiography
  • Emergency Service, Hospital
  • Humans
  • Male
  • Phosphodiesterase 5 Inhibitors / adverse effects*
  • Piperazines / adverse effects*
  • Purines / adverse effects
  • Sildenafil Citrate
  • Sulfones / adverse effects*

Substances

  • Phosphodiesterase 5 Inhibitors
  • Piperazines
  • Purines
  • Sulfones
  • Sildenafil Citrate