Recurrent uveitis due to sildenafil usage in a patient with Behçet's disease

Rheumatol Int. 2013 Mar;33(3):803. doi: 10.1007/s00296-011-2246-7. Epub 2011 Nov 18.

Abstract

Behçet's disease (BD) may cause uveitis and retinal vasculitis in nearly half of the patients. Uveitis is one of the most serious complications that can lead to blindness. Sildenafil (Viagra(R)) and the other phosphodiesterase type 5 (PDE5) inhibitors are the first-line options for the treatment of erectile dysfunction, but transient visual symptoms and serious ocular side effects have been reported in PDE5 inhibitor users. Herein, we report a case with BD who applied to our outpatient unit with recurrent uveitis after sildenafil therapy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Behcet Syndrome / complications*
  • Humans
  • Male
  • Phosphodiesterase 5 Inhibitors / adverse effects*
  • Piperazines / adverse effects*
  • Purines / adverse effects
  • Recurrence
  • Sildenafil Citrate
  • Sulfones / adverse effects*
  • Uveitis / chemically induced*

Substances

  • Phosphodiesterase 5 Inhibitors
  • Piperazines
  • Purines
  • Sulfones
  • Sildenafil Citrate