A case of sensorineural deafness following ingestion of sildenafil

J Laryngol Otol. 2007 Apr;121(4):395-7. doi: 10.1017/S0022215106005512. Epub 2006 Dec 14.

Abstract

We report a case of bilateral profound unremitting sensorineural hearing loss, in a 44-year-old male patient occurring after ingestion of sildenafil citrate 50 mg/day for 15 days. Audiological evaluation documented the findings. Sildenafil is an effective oral treatment for erectile dysfunction syndrome. It is being used and abused by many people as availability is easy and it can even be bought over the internet. Many patients are unaware of the harmful effects of sildenafil and take the drug without medical supervision. We could not find any previously reported cases of sildenafil induced hearing loss and to the best of our knowledge, this is the first case report of sildenafil induced sensorineural hearing loss in the world literature.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Erectile Dysfunction / drug therapy*
  • Hearing Loss, Sensorineural / chemically induced*
  • Humans
  • Male
  • Phosphodiesterase Inhibitors / adverse effects*
  • Piperazines / adverse effects*
  • Purines / adverse effects
  • Sildenafil Citrate
  • Sulfones / adverse effects*

Substances

  • Phosphodiesterase Inhibitors
  • Piperazines
  • Purines
  • Sulfones
  • Sildenafil Citrate