Abstract
Pseudoporphyria is a condition clinically and ultrastructurally identical to porphyria cutanea tarda but with no associated abnormality of heme synthesis. A 45-year-old woman with bullae on the dorsa of her hands was found on investigation to have pseudoporphyria. Her symptoms remitted following the cessation of naproxen therapy.
MeSH terms
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Animals
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Biopsy
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Diagnosis, Differential
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Epidermolysis Bullosa / pathology
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Female
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Hand
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Humans
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Microscopy, Electron
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Microscopy, Fluorescence
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Middle Aged
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Naproxen / adverse effects*
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Porphyrias / chemically induced*
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Porphyrias / pathology
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Porphyrins / blood
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Porphyrins / urine
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Sheep
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Skin / blood supply
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Skin / pathology