PURLs: More isn't better with acute low back pain treatment

J Fam Pract. 2016 Jun;65(6):404-6.

Abstract

Adding cyclobenzaprine or oxycodone/acetaminophen to naproxen for the treatment of acute low back pain does nothing more than increase adverse effects.

Publication types

  • Practice Guideline
  • Research Support, N.I.H., Extramural

MeSH terms

  • Acetaminophen / therapeutic use*
  • Amitriptyline / analogs & derivatives*
  • Amitriptyline / therapeutic use
  • Drug Combinations
  • Female
  • Humans
  • Low Back Pain / drug therapy*
  • Male
  • Muscle Relaxants, Central / therapeutic use*
  • Naproxen / therapeutic use*
  • Oxycodone / therapeutic use*
  • Pain Measurement
  • Randomized Controlled Trials as Topic
  • Treatment Outcome

Substances

  • Drug Combinations
  • Muscle Relaxants, Central
  • oxycodone-acetaminophen
  • Amitriptyline
  • Acetaminophen
  • Naproxen
  • cyclobenzaprine
  • Oxycodone