Abstract
A patient with degenerative joint disease with an unusual hypersensitivity reaction to ibuprofen is described. The patient developed transient fever, myalgia polyarthritis and rash following each of 4 exposures to the drug. These manifestations were associated with positive Coombs' and FANA tests.
MeSH terms
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Antibodies, Antinuclear
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Blood Sedimentation
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Coombs Test
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Drug Hypersensitivity / etiology*
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Female
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Humans
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Ibuprofen / adverse effects*
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Ibuprofen / therapeutic use
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Joint Diseases / drug therapy
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Lupus Erythematosus, Systemic / etiology*
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Middle Aged
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Syndrome
Substances
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Antibodies, Antinuclear
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Ibuprofen