A lupus-like syndrome due to lbuprofen hypersensitivity

J Rheumatol. 1980 May-Jun;7(3):379-80.

Abstract

A patient with degenerative joint disease with an unusual hypersensitivity reaction to ibuprofen is described. The patient developed transient fever, myalgia polyarthritis and rash following each of 4 exposures to the drug. These manifestations were associated with positive Coombs' and FANA tests.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Antinuclear
  • Blood Sedimentation
  • Coombs Test
  • Drug Hypersensitivity / etiology*
  • Female
  • Humans
  • Ibuprofen / adverse effects*
  • Ibuprofen / therapeutic use
  • Joint Diseases / drug therapy
  • Lupus Erythematosus, Systemic / etiology*
  • Middle Aged
  • Syndrome

Substances

  • Antibodies, Antinuclear
  • Ibuprofen