Abstract
A double-blind cross-over study of ketoprofen (Orudis) 150 mg daily and ibuprofen (Brufen) 1,200 mg daily was carried out in 35 outpatients with rheumatoid arthritis. Results suggest that analgesic and anti-inflammatory activity of ketoprofen is superior to that of ibuprofen. Significantly greater pain relief (P < 0.05) and reduction in joint circumference (P < 0.01) was obtained with ketoprofen than with ibuprofen. Side effects of the drugs were comparable and not serious.
Publication types
-
Clinical Trial
-
Comparative Study
-
Randomized Controlled Trial
MeSH terms
-
Acetaminophen / therapeutic use
-
Adult
-
Aged
-
Analgesics / administration & dosage
-
Analgesics / adverse effects
-
Analgesics / therapeutic use*
-
Anti-Inflammatory Agents / administration & dosage
-
Anti-Inflammatory Agents / adverse effects
-
Anti-Inflammatory Agents / therapeutic use*
-
Arthritis, Rheumatoid / drug therapy*
-
Benzoates / administration & dosage
-
Benzoates / adverse effects
-
Benzoates / therapeutic use
-
Clinical Trials as Topic
-
Female
-
Humans
-
Male
-
Middle Aged
-
Pain / drug therapy
-
Phenylpropionates / administration & dosage
-
Phenylpropionates / adverse effects
-
Phenylpropionates / therapeutic use*
Substances
-
Analgesics
-
Anti-Inflammatory Agents
-
Benzoates
-
Phenylpropionates
-
Acetaminophen