Acute localized exanthematous pustulosis (ALEP) caused by Ibuprofen. A case report

Br J Oral Maxillofac Surg. 2009 Mar;47(2):132-4. doi: 10.1016/j.bjoms.2008.07.185. Epub 2008 Sep 9.

Abstract

Acute generalized exanthematic pustulosis (AGEP) is characterized by a generalized rash and sterile disseminated, sometimes coalescing subcorneal pustules. It occurs in body flexures such as the inguinal folds and intertriginous areas. The acute onset of disease is accompanied by malaise, fever >38 degrees C and peripheral granulocytosis. We report on a female patient who according to the criteria of AGEP was diagnosed as having acute localized exanthematic pustulosis (ALEP) on the face.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Anti-Inflammatory Agents, Non-Steroidal / administration & dosage*
  • Drug Eruptions / etiology*
  • Exanthema / chemically induced*
  • Facial Dermatoses / chemically induced*
  • Female
  • Humans
  • Ibuprofen / adverse effects*
  • Middle Aged

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Ibuprofen