Relapsed hydroxychloroquine induced thrombocytopenia in a systemic lupus erythematosus patient

Reumatol Clin. 2017 Sep-Oct;13(5):294-296. doi: 10.1016/j.reuma.2016.04.008. Epub 2016 Jun 2.
[Article in English, Spanish]

Abstract

Hydroxychloroquine is used in the long-term therapy of systemic lupus erythematosus (SLE). Although considered to be a safe treatment, side effects have been documented. An uncommon side effect is thrombocytopenia. In order to establish the diagnosis of thrombocytopenia secondary to Hydroxychloroquine, non-pharmacological causes must be ruled out and it is necessary to determine a recurrence after re-exposure to the drug. We present one case of severe thrombocytopenia occurring in a patient with SLE undergoing treatment with Hydroxychloroquine.

Keywords: Hidroxicloroquina; Hydroxychloroquine; Lupus eritematoso sistémico; Systemic lupus erythematosus; Thrombocytopenia; Trombocitopenia.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antirheumatic Agents / adverse effects*
  • Antirheumatic Agents / therapeutic use
  • Humans
  • Hydroxychloroquine / adverse effects*
  • Hydroxychloroquine / therapeutic use
  • Lupus Erythematosus, Systemic / complications
  • Lupus Erythematosus, Systemic / drug therapy*
  • Male
  • Recurrence
  • Thrombocytopenia / chemically induced*
  • Thrombocytopenia / diagnosis

Substances

  • Antirheumatic Agents
  • Hydroxychloroquine