Abstract
Acute generalized exanthematous pustulosis (AGEP) is a severe cutaneous adverse reaction, mostly induced by drugs. Hydroxychloroquine have been rarely reported in literature as a causative drug of this reaction. We report a case of AGEP induced by hydroxychloroquine with systemic involvement and confirmed by positive patch testing.
Keywords:
Hydroxychloroquine; patch test; pustulosis.
MeSH terms
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Acute Generalized Exanthematous Pustulosis / diagnosis
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Acute Generalized Exanthematous Pustulosis / etiology*
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Adult
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Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
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Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
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Arthralgia / etiology
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Arthralgia / prevention & control
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Chloroquine / adverse effects
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Chloroquine / therapeutic use
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Drug Monitoring
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Drug Resistance
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Drug Therapy, Combination / adverse effects
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Female
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Humans
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Hydroxychloroquine / adverse effects*
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Hydroxychloroquine / therapeutic use
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Lupus Erythematosus, Systemic / drug therapy
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Lupus Erythematosus, Systemic / physiopathology
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Patch Tests
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Prednisolone / adverse effects
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Prednisolone / therapeutic use
Substances
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Anti-Inflammatory Agents, Non-Steroidal
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Hydroxychloroquine
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Chloroquine
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Prednisolone