A fatal complication after repair of post-infarction ventricular septal rupture: heparin-induced thrombocytopenia with thrombosis

Yunus Nazli; Necmettin Colak; Bora Demircelik; Mehmet Faith Alpay; Omer Cakir; Kerim Cagli

doi:10.5830/CVJA-2015-001

A fatal complication after repair of post-infarction ventricular septal rupture: heparin-induced thrombocytopenia with thrombosis

Cardiovasc J Afr. 2015 May 23;26(3):e11-5. doi: 10.5830/CVJA-2015-001.

Authors

Yunus Nazli¹, Necmettin Colak¹, Bora Demircelik², Mehmet Faith Alpay¹, Omer Cakir¹, Kerim Cagli³

Affiliations

¹ Department of Cardiovascular Surgery, Faculty of Medicine, University of Turgut Ozal, Ankara, Turkey.
² Department of Cardiology, Faculty of Medicine, University of Turgut Ozal, Ankara, Turkey.
³ Department of Cardiovascular Surgery, Turkiye Yuksek Ihtisas Hospital, Ankara, Turkey.

Abstract

Heparin-induced thrombocytopenia (HIT) is a rare but potentially devastating and life-threatening complication from using heparin. HIT not only causes thrombocytopenia, but it also carries an increased risk for fatal thrombotic complications. In this report, we describe the case of a patient in whom fatal HIT developed after successful surgical repair of a posterior post-infarction ventricular septal rupture with cardiopulmonary bypass.

Publication types

Case Reports

MeSH terms

Aged
Anticoagulants / adverse effects*
Cardiac Surgical Procedures*
Cardiopulmonary Bypass
Coronary Angiography
Coronary Artery Bypass
Fatal Outcome
Heparin / adverse effects*
Humans
Male
Myocardial Infarction / complications*
Myocardial Infarction / diagnosis
Myocardial Infarction / surgery
Suture Techniques
Thrombocytopenia / chemically induced*
Thrombocytopenia / diagnosis
Thrombosis / chemically induced*
Thrombosis / diagnosis
Time Factors
Treatment Outcome
Ventricular Septal Rupture / diagnosis
Ventricular Septal Rupture / etiology
Ventricular Septal Rupture / surgery*

Substances

Anticoagulants
Heparin