Heparin-induced thrombocytopenia and warfarin-induced skin necrosis: case report

An Bras Dermatol. 2010 Nov-Dec;85(6):915-8. doi: 10.1590/s0365-05962010000600024.
[Article in English, Portuguese]

Abstract

This paper describes a case of heparin-induced thrombocytopenia complicated by warfarin-induced skin necrosis in a 74-year old female patient hospitalized with diagnoses of a hip fracture, deep vein thrombosis and pulmonary thromboembolism. Warfarin-induced skin necrosis is a rare complication of anticoagulant therapy, with high morbidity and mortality that may be associated with heparin-induced thrombocytopenia.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anticoagulants / adverse effects*
  • Female
  • Heparin / adverse effects*
  • Humans
  • Necrosis / chemically induced
  • Skin / pathology*
  • Thrombocytopenia / chemically induced*
  • Warfarin / adverse effects*

Substances

  • Anticoagulants
  • Warfarin
  • Heparin