Following BCG vaccination, local or systemic complications may occur. A 19-year-old female patient with negative tuberculin skin test developed a blister evolving over two weeks into an ulcer in a vaccination site on the left hip. Ulcerations following BCG vaccination are rare and show a tendency to chronicity. The treatment recommendations are controversial and range from non-specific topical treatment to systemic tuberculostatic therapy. In this case, the ulcer cleared rapidly after topical treatment with INH powder.