Case Report: Steroid-induced Ocular Hypertension in a 6-year-old Boy

Optom Vis Sci. 2021 Aug 1;98(8):867-869. doi: 10.1097/OPX.0000000000001747.

Abstract

Significance: Systemic corticosteroid use in children is rare because of known risks of adverse effects. The increased prevalence of multisystem inflammatory syndrome associated with COVID-19 may change this. It is critical for eye care providers to be aware of potential severe and rapid ocular hypertensive response to prevent irreversible vision loss.

Purpose: The purpose of this study was to report the importance of early monitoring of intraocular eye pressure in pediatric patients on systemic steroid medication.

Case report: A 6-year-old White boy presented with a complaint of headache for 2 weeks. He was on his 19th day of treatment for acute lymphoblastic leukemia with oral dexamethasone and chemotherapy. IOP at presentation was 65 mmHg in both eyes measured with iCare tonometry. Treatment with maximum topical glaucoma therapy reduced IOP to normal levels and eliminated the symptom of headache.

Conclusions: This case reminds eye care providers to be aware of the potential ocular hypertensive response to systemic steroid treatment and the importance of establishing early monitoring. With the emergence of multisystem inflammatory syndrome in children during the current COVID-19 pandemic, eye care providers may encounter more pediatric patients on systemic corticosteroid treatment than previously and should adjust their examinations appropriately.

Publication types

  • Case Reports

MeSH terms

  • COVID-19*
  • Child
  • Glaucoma* / chemically induced
  • Glaucoma* / diagnosis
  • Glaucoma* / drug therapy
  • Humans
  • Intraocular Pressure
  • Male
  • Ocular Hypertension* / chemically induced
  • Ocular Hypertension* / diagnosis
  • Pandemics
  • SARS-CoV-2
  • Steroids
  • Systemic Inflammatory Response Syndrome
  • Tonometry, Ocular

Substances

  • Steroids

Supplementary concepts

  • pediatric multisystem inflammatory disease, COVID-19 related