Hemopericardium and cardiac tamponade as presenting findings of dexamethasone-induced hypertrophic cardiomyopathy complicated by transmural myocardial infarction

L D Lilien; R H Lilien; S Setrakian

doi:10.1007/s00246-002-0159-7

Hemopericardium and cardiac tamponade as presenting findings of dexamethasone-induced hypertrophic cardiomyopathy complicated by transmural myocardial infarction

Pediatr Cardiol. 2003 May-Jun;24(3):280-3. doi: 10.1007/s00246-002-0159-7. Epub 2003 Mar 14.

Authors

L D Lilien¹, R H Lilien, S Setrakian

Affiliation

¹ Neonatology Associates, 300 W. Clarendon, No. 375, Phoenix, AZ 85013, USA.

PMID: 12632228
DOI: 10.1007/s00246-002-0159-7

Abstract

This is the first report of dexamethasone-induced left ventricular outflow obstruction causing decreased coronary artery perfusion and apical transmural cardiac infarct that resulted in hemopericardium and rapid cardiac tamponade. The differential diagnosis of hemorrhagic pericardial effusion must now include dexamethasone-induced hypertrophic cardiomyopathy.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Anti-Inflammatory Agents / adverse effects*
Cardiac Tamponade / etiology*
Cardiomyopathy, Hypertrophic / chemically induced*
Coronary Circulation / physiology
Dexamethasone / adverse effects*
Diseases in Twins*
Fatal Outcome
Humans
Infant, Newborn
Infant, Premature*
Male
Myocardial Infarction / etiology*
Pericardial Effusion / etiology*
Ventricular Outflow Obstruction / chemically induced*

Substances

Anti-Inflammatory Agents
Dexamethasone