Relief of pain in acute herpes zoster by nerve blocks and possible prevention of post-herpetic neuralgia

Can J Anaesth. 2005 Feb;52(2):186-90. doi: 10.1007/BF03027727.

Abstract

Purpose: This report describes two cases of acute herpes zoster (AHZ) treated by nerve block resulting in immediate pain relief and possible prevention of post-herpetic neuralgia (PHN).

Clinical features: Two elderly females with AHZ of cervical dermatomes and severe pain received deep cervical and greater occipital nerve blocks with a local anesthetic, epinephrine and steroid. In both patients, pain resolved immediately and permanently (one year follow-up) after a single treatment. Case #1: A 79-yr-old female with a mechanical mitral valve and anticoagulated with warfarin presented with AHZ of 17 days duration of the right C2, 3, 4 dermatomes and severe pain. A stellate ganglion block was not performed because of anticoagulation. Rather, a deep cervical root block at C3 and a greater occipital nerve block were performed with bupivacaine, epinephrine and methylprednisolone. No adverse events were evident. Case #2: A 73-yr-old female with a history of osteoarthritis and Meniere's disease presented with AHZ of seven days duration of the left C2, 3, 4 dermatomes and severe pain. Deep cervical root blocks at C3 and C4 and a greater occipital nerve block were performed with bupivacaine, epinephrine and methylprednisolone. Side effects of dizziness, hoarseness, hypertension and Horner's syndrome resolved in a few hours. A mild sensation of itching persisted for two weeks.

Conclusion: This report illustrates the potential of nerve blocks in severe AHZ to treat acute pain and possibly prevent PHN.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anesthetics, Local / administration & dosage
  • Anesthetics, Local / adverse effects
  • Anesthetics, Local / therapeutic use
  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / adverse effects
  • Anti-Inflammatory Agents / therapeutic use
  • Bupivacaine / administration & dosage
  • Bupivacaine / adverse effects
  • Bupivacaine / therapeutic use
  • Epinephrine / administration & dosage
  • Epinephrine / adverse effects
  • Epinephrine / therapeutic use
  • Female
  • Herpes Zoster / complications*
  • Humans
  • Methylprednisolone / administration & dosage
  • Methylprednisolone / adverse effects
  • Methylprednisolone / therapeutic use
  • Nerve Block*
  • Neuralgia / etiology
  • Neuralgia / prevention & control*
  • Oculomotor Nerve
  • Pain / drug therapy*
  • Pain / etiology*
  • Vasoconstrictor Agents / administration & dosage
  • Vasoconstrictor Agents / adverse effects
  • Vasoconstrictor Agents / therapeutic use

Substances

  • Anesthetics, Local
  • Anti-Inflammatory Agents
  • Vasoconstrictor Agents
  • Methylprednisolone
  • Bupivacaine
  • Epinephrine