Do we miss rare adverse events induced by COVID-19 vaccination?

Zeinab Mohseni Afshar; Ali Tavakoli Pirzaman; Jackson J Liang; Akanksha Sharma; Marzieh Pirzadeh; Arefeh Babazadeh; Erfan Hashemi; Niloofar Deravi; Sadaf Abdi; Amirreza Allahgholipour; Rezvan Hosseinzadeh; Zahra Vaziri; Terence T Sio; Mark J M Sullman; Mohammad Barary; Soheil Ebrahimpour

doi:10.3389/fmed.2022.933914

Do we miss rare adverse events induced by COVID-19 vaccination?

Front Med (Lausanne). 2022 Oct 10:9:933914. doi: 10.3389/fmed.2022.933914. eCollection 2022.

Authors

Zeinab Mohseni Afshar¹, Ali Tavakoli Pirzaman², Jackson J Liang³, Akanksha Sharma⁴, Marzieh Pirzadeh², Arefeh Babazadeh⁵, Erfan Hashemi², Niloofar Deravi⁶, Sadaf Abdi², Amirreza Allahgholipour⁷, Rezvan Hosseinzadeh², Zahra Vaziri², Terence T Sio⁸, Mark J M Sullman^{9

10}, Mohammad Barary^{11

12}, Soheil Ebrahimpour⁵

Affiliations

¹ Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
² Student Research Committee, Babol University of Medical Sciences, Babol, Iran.
³ Division of Cardiovascular Medicine, Cardiac Arrhythmia Service, University of Michigan, Ann Arbor, MI, United States.
⁴ Department of Neurology, Mayo Clinic, Scottsdale, AZ, United States.
⁵ Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.
⁶ Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
⁷ Student Research Committee, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
⁸ Department of Radiation Oncology, Mayo Clinic, Phoenix, AZ, United States.
⁹ Department of Social Sciences, University of Nicosia, Nicosia, Cyprus.
¹⁰ Department of Life and Health Sciences, University of Nicosia, Nicosia, Cyprus.
¹¹ Student Research Committee, Virtual School of Medical Education and Management, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
¹² Students' Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran.

Abstract

Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has caused many complications, the invention of coronavirus disease 2019 (COVID-19) vaccines has also brought about several adverse events, from common side effects to unexpected and rare ones. Common vaccine-related adverse reactions manifest locally or systematically following any vaccine, including COVID-19 vaccines. Specific side effects, known as adverse events of particular interest (AESI), are unusual and need more evaluation. Here, we discuss some of the most critical rare adverse events of COVID-19 vaccines.

Keywords: COVID-19; SARS-CoV-2; drug-related side effects and adverse reactions; pandemic (COVID-19); vaccination.

Publication types

Review