Kidney Injury in Patients Treated with Immune Checkpoint Inhibitors Does Not Meet KDIGO-AKI Criteria

Maartje F A Verploegen; Marye J Boers-Sonderen; Berber Piet; Jack F M Wetzels

doi:10.34067/KID.0006752021

Kidney Injury in Patients Treated with Immune Checkpoint Inhibitors Does Not Meet KDIGO-AKI Criteria

Kidney360. 2021 Dec 21;3(3):524-529. doi: 10.34067/KID.0006752021. eCollection 2022 Mar 31.

Authors

Maartje F A Verploegen¹, Marye J Boers-Sonderen², Berber Piet³, Jack F M Wetzels¹

Affiliations

¹ Department of Nephrology, Radboud University Medical Center, Nijmegen, The Netherlands.
² Department of Medical Oncology, Radboud University Medical Center, Nijmegen, The Netherlands.
³ Department of Pulmonary Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.

Abstract

Kidney injury in patients treated with immune checkpoint inhibitors develops gradually and often does not meet the Kidney Disease Improving Global Outcomes criteria for AKI.Proper classification of kidney injury could prevent the development of CKD and improve continued oncologic treatment.

Keywords: KDIGO; acute kidney injury; clinical nephrology; immune checkpoint inhibitors.

MeSH terms

Acute Kidney Injury* / chemically induced
Humans
Immune Checkpoint Inhibitors* / adverse effects
Incidence
Kidney

Substances

Immune Checkpoint Inhibitors