A case of pemphigus vulgaris possibly triggered by quinolones

J Eur Acad Dermatol Venereol. 2002 Mar;16(2):152-3. doi: 10.1046/j.1468-3083.2002.00393.x.

Abstract

Pemphigus vulgaris is an autoimmune blistering disorder in which both genetic and environmental factors, mainly drugs, are thought to play a part in its aetiopathogenesis. Although some drugs that contain thiol groups, such as D-penicillamine and captopril, and non-thiol drugs, such as cephalosporin, have been reported to trigger or induce pemphigus, there are no previous reports regarding the influence of quinolones in triggering this disease. Here we present a case of pemphigus possibly triggered by quinolones.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Azathioprine / administration & dosage
  • Biopsy, Needle
  • Ciprofloxacin / adverse effects*
  • Ciprofloxacin / therapeutic use
  • Drug Therapy, Combination
  • Follow-Up Studies
  • Humans
  • Male
  • Mouth Mucosa / pathology
  • Pemphigus / chemically induced*
  • Pemphigus / drug therapy
  • Pemphigus / pathology
  • Prednisolone / administration & dosage
  • Quinolones / adverse effects*
  • Quinolones / therapeutic use
  • Risk Assessment
  • Severity of Illness Index
  • Treatment Outcome
  • Urinary Tract Infections / diagnosis
  • Urinary Tract Infections / drug therapy*

Substances

  • Quinolones
  • Ciprofloxacin
  • Prednisolone
  • Azathioprine