Case: Unexpected development of severe penicillin allergy and review of literature

Rauno J Harvima; Ilkka T Harvima

doi:10.1002/ccr3.5248

Case: Unexpected development of severe penicillin allergy and review of literature

Clin Case Rep. 2022 Jan 20;10(1):e05248. doi: 10.1002/ccr3.5248. eCollection 2022 Jan.

Authors

Rauno J Harvima¹, Ilkka T Harvima¹

Affiliation

¹ Department of Dermatology Kuopio University Hospital and University of Eastern Finland Kuopio Finland.

Abstract

A 54-year-old man developed a severe anaphylactic penicillin allergy after 16 years and 5 standard erysipelas treatments by intravenous benzylpenicillin and/or oral phenoxymethylpenicillin without any symptoms of allergy. It is recommended to analyze specific IgE antibodies for phenoxymethylpenicillin, benzylpenicillin, amoxicillin, and cefaclor to select an appropriate antibiotic.

Keywords: amoxicillin; benzylpenicillin; cefaclor; penicillin allergy; phenoxymethylpenicillin; specific IgE.

Publication types

Case Reports