[Cortisone glaucoma: epidemiological, clinical, and therapeutic study]

J Fr Ophtalmol. 2007 Jan;30(1):49-52. doi: 10.1016/s0181-5512(07)89550-7.
[Article in French]

Abstract

Introduction: Cortisone glaucoma is a secondary glaucoma induced by local or oral steroids used to treat chronic inflammatory diseases.

Patients and methods: Retrospective study including 43 eyes of 23 patients (three patients were monophthalmos). We present epidemiological and clinical features with evaluation of functional damage (visual acuity, visual field), and therapeutic results with a follow-up period ranging from 2 to 10 years.

Results: Topical steroids were incriminated in 15 of 23 cases (self-medication), whereas general steroids (for chronic diseases) were used by eight patients. Visual function was seriously affected (visual acuity<1/10 in 23/43 eyes at the first visit with pronounced visual field abnormalities). Surgery was necessary in 16 of 43 eyes (deep sclerectomy with or without implant, trabeculectomy).

Discussion: Cortisone glaucoma is rather frequent in Tunisia where conjunctival allergy and self-medication are common. Young adults are concerned, making it a high surgical risk usually requiring surgical devices such as a T Flux implant.

Conclusion: Cortisone glaucoma is a serious complication of steroid therapy that usually affects young adults. The disease is usually detected late, explaining the severe functional damage.

Publication types

  • English Abstract

MeSH terms

  • Administration, Topical
  • Adolescent
  • Adrenal Cortex Hormones / administration & dosage
  • Adrenal Cortex Hormones / adverse effects*
  • Adult
  • Autoimmune Diseases / drug therapy
  • Cataract / chemically induced
  • Child
  • Conjunctivitis, Allergic / drug therapy
  • Female
  • Glaucoma / chemically induced*
  • Glaucoma / epidemiology
  • Glaucoma / surgery
  • Glaucoma Drainage Implants
  • Humans
  • Male
  • Retrospective Studies
  • Sclera / surgery
  • Trabeculectomy
  • Tunisia / epidemiology
  • Visual Acuity
  • Visual Fields

Substances

  • Adrenal Cortex Hormones