Promethazine
- TRADE NAMES: Anergan; Atosil; Bonnox; Closin; Goodnight; Histantil; Pentazine; Phenazine; Phenergan (Wyeth); Prometh-50; Prothiazine; Pyrethia
- INDICATIONS: Allergic rhinitis, urticaria
- CLASS: Histamine H1 receptor antagonist
- HALF-LIFE: 10–14 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Antihistamines, Arsenic, Chlorpheniramine, Dofetilide, Nalbuphine, Piperazine, Quinolones, Sparfloxacin, Zaleplon
PREGNANCY CATEGORY: C
Not for intra-arterial or subcutaneous injection and contra-indicated in comatose states.
RESPIRATORY DEPRESSION and SEVERE TISSUE INJURY, INCLUDING GANGRENE
See full prescribing information for complete boxed warning.
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SKIN.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
GASTROINTESTINAL/HEPATIC.
HEMATOLOGIC.
LOCAL.
NEUROMUSCULAR/SKELETAL.
OTHER.
Page last updated 07/31/2023
Symbol key
Incidence
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric