Pneumatosis cystoides intestinalis in neuropsychiatric systemic lupus erythematosus with diabetes mellitus: case report and literature review

Mod Rheumatol. 2011 Aug;21(4):415-9. doi: 10.1007/s10165-010-0407-2. Epub 2011 Jan 15.

Abstract

We report a patient with neuropsychiatric systemic lupus erythematosus (NPSLE) complicated by diabetes mellitus (DM) who showed pneumatosis cystoides intestinalis (PCI) while being treated with prednisolone (PSL) and an alpha-glucosidase inhibitor (αGI). The PCI was ameliorated with the cessation of the αGI and tapering of PSL in addition to transient fasting. Multiple factors, including NPSLE, DM, and medications, may have been involved in the pathogenesis of PCI in this patient.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Diabetes Complications / drug therapy*
  • Drug Therapy, Combination
  • Glucocorticoids / administration & dosage
  • Glucocorticoids / adverse effects
  • Humans
  • Hypoglycemic Agents / administration & dosage
  • Hypoglycemic Agents / adverse effects
  • Inositol / administration & dosage
  • Inositol / adverse effects
  • Inositol / analogs & derivatives*
  • Lupus Vasculitis, Central Nervous System / drug therapy*
  • Male
  • Middle Aged
  • Pneumatosis Cystoides Intestinalis / chemically induced*
  • Pneumatosis Cystoides Intestinalis / diagnostic imaging
  • Prednisolone / administration & dosage
  • Prednisolone / adverse effects*
  • Sulfonylurea Compounds / administration & dosage
  • Sulfonylurea Compounds / adverse effects*
  • Tomography, X-Ray Computed

Substances

  • Glucocorticoids
  • Hypoglycemic Agents
  • Sulfonylurea Compounds
  • Inositol
  • glimepiride
  • Prednisolone
  • voglibose