Carbamazepine

  • TRADE NAME: Apo-Carbamazepine; Atreol; Carbatrol; Epitol (Teva); Foxsalepsin; Kodapan; Lexin; Mazepine; Sirtal; Tegretol (Novartis); Tegretol XR; Teril; Timonil
  • INDICATIONS: Epilepsy, pain or trigeminal neuralgia
  • CLASS: Anticonvulsant, Antipsychotic, Mood stabilizer
  • HALF-LIFE: 18–55 hours

PREGNANCY CATEGORY: D

Aromatic antiepileptic drugs, phenytoin, phenobarbital, carbamazepine and primidone, are a frequent cause of severe cutaneous adverse reactions. A strong genetic association between HLA-B*1502 and carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis has been shown in Han Chinese patients.

Our database has 119 adverse reactions for this drug across the following areas

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SKIN
HAIR
NAILS
MUCOSAL
CARDIOVASCULAR
CENTRAL NERVOUS SYSTEM
NEUROMUSCULAR/SKELETAL
GASTROINTESTINAL/HEPATIC
ENDOCRINE/METABOLIC
RENAL
HEMATOLOGIC
OTIC
OCULAR
OTHER
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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life Threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric