Topotecan

  • TRADE NAME: Hycamtin (GSK)
  • INDICATIONS: Metastatic ovarian carcinoma
  • CLASS: Topoisomerase 1 inhibitor, Antineoplastic
  • HALF-LIFE: 3 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Atorvastatin, Lapatinib, Pantoprazole

PREGNANCY CATEGORY: D

Our database has 31 adverse reactions for this drug across the following areas

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SKIN
HAIR
NAILS
MUCOSAL
CENTRAL NERVOUS SYSTEM
NEUROMUSCULAR/SKELETAL
GASTROINTESTINAL/HEPATIC
RESPIRATORY
RENAL
HEMATOLOGIC
OTHER
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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life Threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric