Spironolactone

  • TRADE NAME: Aldactazide (Pfizer); Aldactone (Pfizer); Aldopur; Almatol; Diram; Merabis; Novo-Spiroton; Osiren; Spiroctan; Tensin
  • INDICATIONS: Hyperaldosteronism, hirsutism, hypertension
  • CLASS: Aldosterone antagonist, Diuretic
  • HALF-LIFE: 78–84 minutes
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

ACE inhibitors, Alcohol, Amiloride, Barbiturates, Benazepril, Captopril, Cyclosporine, Enalapril, Fosinopril, Juniper, Lisinopril, Mitotane, Moexipril, Narcotics, NSAIDs, Potassium chloride, Potassium Iodide, Quinapril, Ramipril, Trandolapril, Triamterene, Zofenopril

PREGNANCY CATEGORY: C

NOTE

Aldactazide is spironolactone and hydrochlorothiazide

Our database has 49 adverse reactions for this drug across the following areas

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SKIN
HAIR
MUCOSAL
CARDIOVASCULAR
CENTRAL NERVOUS SYSTEM
ENDOCRINE/METABOLIC
RENAL
OTHER
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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life Threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric