Captopril

BreastfeedingPediatric
  • TRADE NAMES: Acenorm; Acepril; Adocor; APO-Capto; Capoten (Par); Capozide (Par); Captolane; Captoril; Lopirin; Lopril; Nu-Capto; Precaptil
  • INDICATIONS: Hypertension, congestive heart failure, to improve survival following myocardial infarction in clinically stable patients with left ventricular dysfunction, diabetic nephropathy in patients with Type I insulin-dependent diabetes mellitus and retinopathy
  • CLASS: Angiotensin-converting enzyme (ACE) inhibitor, Antihypertensive, Vasodilator
  • HALF-LIFE: <3 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Alcohol, Aldesleukin, Allopurinol, Alpha blockers, Alprostadil, Amifostine, Amiloride, Angiotensin II receptor antagonists, Antacids, Antidiabetics, Antihypertensives, Antipsychotics, Anxiolytics and hypnotics, Aprotinin, Azathioprine, Baclofen, Beta blockers, Calcium channel blockers, Clonidine, Cyclosporine, CYP2D6 inhibitors, Darunavir, Diazoxide, Digoxin, Diuretics, Eplerenone, Estrogens, Everolimus, General anesthetics, Gold & Gold Compounds, Heparins, Herbals, Hydralazine, Hypotensives, Insulin, Interferon Alfa, Levodopa, Lithium, MAO inhibitors, Metformin, Methyldopa, Methylphenidate, Minoxidil, Moxisylyte, Moxonidine, Naldemedine, Nitrates, Nitroprusside, NSAIDs, Pentoxifylline, Phosphodiesterase 5 inhibitors, Potassium salts, Probenecid, Prostacyclin analogues, Rituximab, Salicylates, Sirolimus, Spironolactone, Sulfonylureas, Temsirolimus, Tizanidine, Tolvaptan, Triamterene, Trimethoprim, Venetoclax, Yohimbine

PREGNANCY CATEGORY: D
category C in first trimester; category D in second and third trimesters

Capozide is captopril and hydrochlorothiazide.

Hydrochlorothiazide is a sulfonamide and can be absorbed systemically. Sulfonamides can produce severe, possibly fatal, reactions such as toxic epidermal necrolysis and Stevens-Johnson syndrome.

FETAL TOXICITY

See full prescribing information for complete boxed warning.

Our database has 88 adverse reactions for this drug across the following areas

Please login to see the rest of this drug profile


Not a subscriber? Click here to subscribe

SKIN
HAIR
NAILS
MUCOSAL
CARDIOVASCULAR
CENTRAL NERVOUS SYSTEM
NEUROMUSCULAR/SKELETAL
GASTROINTESTINAL/HEPATIC
RESPIRATORY
ENDOCRINE/METABOLIC
RENAL
HEMATOLOGIC
OCULAR
OTHER


Page last updated 10/17/2017

Drug Eruption Mobile Site

Symbol key

Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric