Bismuth
- TRADE NAMES: Bismatrol; Bismuth Iodoform Paraffin Paste (BIPP); Bismuth subcitrate; Bismuth subgallate; Bismuth sucralfate; Caved-S; Colo-Fresh; De-Nol; Devrom; Diotame; Helidac (Prometheus); Pepto-Bismol (Procter & Gamble); Pink Bismuth
- INDICATIONS: As part of ‘triple therapy’ (antibiotics + bismuth) for eradication of H. pylori. Bismuth subgallate initiates clotting via activation of factor XII, and is used for bleeding during tonsillectomy and adenoidectomy. BIPP impregnated ribbon gauze is used for packing following ear surgery. Bismuth subsalicylate is in OTC products for gastrointestinal complaints and peptic ulcer disease.
- CLASS: Disinfectant, Heavy metal
- HALF-LIFE: 21–72 days
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Aspirin, Ciprofloxacin, Demeclocycline, Doxycycline, Hypoglycemics, Lomefloxacin, Lymecycline, Methotrexate, Minocycline, Tetracycline, Warfarin
PREGNANCY CATEGORY: D
category C in first and second trimesters; category D in third trimester
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SKIN.
HAIR.
MUCOSAL.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
LOCAL.
NEUROMUSCULAR/SKELETAL.
OTIC.
RENAL.
OTHER.
Page last updated 07/31/2023
Symbol key
Incidence
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric