Oxycodone
- TRADE NAMES: Endocodone; OxyContin (Purdue); OxyIR (Purdue); Percocet (Endo); Roxicodone (aaiPharma); Supeudol; Targiniq (Purdue); Troxyca (Pfizer); Tylox (Ortho-McNeil); Xtampza ER (Collegium)
- INDICATIONS: Pain
- CLASS: Opiate agonist
- HALF-LIFE: 4.6 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Cimetidine, Clonazepam, Telithromycin, Voriconazole
PREGNANCY CATEGORY: B
Oxycodone is often combined with acetaminophen (Percocet, Roxicet, Tylox) or aspirin (Percodan, Roxiprin); Targiniq is oxycodone and naloxone; Troxyca is oxycodone and naltrexone.
Contra-indicated in patients with significant respiratory depression, acute or severe bronchial asthma, or with known or suspected gastrointestinal obstruction, including paralytic ileus.
ADDICTION, ABUSE and MISUSE; LIFE-THREATENING RESPIRATORY DEPRESSION; ACCIDENTAL INGESTION; NEONATAL OPIOID WITHDRAWAL SYNDROME; and CYTOCHROME P450 3A4 INTERACTION
See full prescribing information for complete boxed warning.
Please login to see the rest of this drug profile
SKIN.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
LOCAL.
NEUROMUSCULAR/SKELETAL.
RESPIRATORY.
OTHER.
Page last updated 07/31/2023
Symbol key
Incidence
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric