Acetaminophen
- TRADE NAMES: Anacin-3 (Wyeth); Darvocet-N (aaiPharma); Excedrin (Bristol-Myers Squibb); Geluprane; Liquiprin; Lorcet (Forest); Mapap; Neopap; Ofirmev; Panadol (GSK); Paracetamol; Percocet (Endo); Percogesic; Phenaphen; Sinutab; Tylenol (Ortho-McNeil); Valadol; Vicodin (AbbVie)
- INDICATIONS: Pain, fever
- SYNONYM: APAP; paracetamol
- CLASS: Analgesic; non-narcotic
- HALF-LIFE: <3 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Alcohol, Anticonvulsants, Barbiturates, Busulfan, Carbamazepine, Cholestyramine, Conivaptan, Coumarins, Didanosine, Dong Quai, Exenatide, Imatinib, Isoniazid, Liraglutide, Melatonin, Metoclopramide, Metyrapone, PEG-Interferon, Pramlintide, Probenecid, St John's Wort
PREGNANCY CATEGORY: C
Acetaminophen is the active metabolite of phenacetin.
[IV] = intravenous.
As a general point most reactions listed are those that have developed following the normal prescribing doses for acetaminophen and the overdosing, poisoning, and other toxicities that have been reported have been excluded.
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SKIN.
NAILS.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
HEMATOLOGIC.
NEUROMUSCULAR/SKELETAL.
OCULAR.
OTIC.
RENAL.
RESPIRATORY.
OTHER.
Page last updated 01/07/2024
Symbol key
Incidence
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric