Linezolid

Breastfeeding
  • TRADE NAME: Zyvox (Pfizer)
  • INDICATIONS: Various infections caused by susceptible organisms
  • CLASS: Antibiotic, oxazolidinone
  • HALF-LIFE: 4–5 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Alcohol, Alpha blockers, Altretamine, Amitriptyline, Amoxapine, Amphetamines, Anilidopiperidine opioids, Antihypertensives, Atomoxetine, Beta blockers, Buprenorphine, Bupropion, Buspirone, Caffeine, Carbamazepine, Clomipramine, Cyclobenzaprine, Desipramine, Desvenlafaxine, Dexmethylphenidate, Dextromethorphan, Diethylpropion, Doxapram, Doxepin, Fluoxetine, Fluvoxamine, Hydromorphone, Imipramine, Levodopa, Lithium, MAO inhibitors, Maprotiline, Meperidine, Methadone, Methyldopa, Methylphenidate, Mirtazapine, Nortriptyline, Oral typhoid vaccine, Paroxetine Hydrochloride, Propoxyphene, Protriptyline, Reserpine, Rifampin, Safinamide, Serotonin 5-HT1D receptor agonists, Serotonin/norepinephrine reuptake inhibitors, Sertraline, Sibutramine, SSRIs, Tapentadol, Tetrabenazine, Tetrahydrozoline, Tramadol, Trazodone, Tricyclic antidepressants, Trimipramine, Tryptophan, Venlafaxine

PREGNANCY CATEGORY: C

Our database has 83 adverse reactions for this drug across the following areas

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SKIN
MUCOSAL
CENTRAL NERVOUS SYSTEM
NEUROMUSCULAR/SKELETAL
GASTROINTESTINAL/HEPATIC
RESPIRATORY
ENDOCRINE/METABOLIC
GENITOURINARY
RENAL
HEMATOLOGIC
OCULAR
LOCAL
OTHER


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Click on the DRUG REVIEW ARTICLE tab (above) to see a review of linezolid in the Taylor & Francis journal Expert Opinion on Drug Safety. (Note that non-subscribers to the journal will only be able to see an abstract of the article.)

Page last updated 10/02/2017

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric