Irbesartan

BreastfeedingPediatric
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

ACE inhibitors, Adrenergic neurone blockers, Alcohol, Aldesleukin, Aldosterone antagonists, Aliskiren, Alpha blockers, Alprostadil, Amifostine, Antihypertensives, Antipsychotics, Anxiolytics and hypnotics, Baclofen, Beta blockers, Calcium channel blockers, Carvedilol, Clonidine, Corticosteroids, Cyclosporine, CYP2C8 and CYP2C9 substrates, Diazoxide, Diuretics, Eplerenone, Fluconazole, General anesthetics, Heparins, Hypotensives, Levodopa, Lithium, MAO inhibitors, Methyldopa, Methylphenidate, Moxisylyte, Moxonidine, Nitrates, NSAIDs, Pentoxifylline, Phosphodiesterase 5 inhibitors, Potassium salts, Prostacyclin analogues, Rifamycin derivatives, Rituximab, Tacrolimus, Tizanidine, Tolvaptan, Trimethoprim

PREGNANCY CATEGORY: D
category C in first trimester; category D in second and third trimesters

Avalide is irbesartan and hydrochlorothiazide.

Hydrochlorothiazide is a sulfonamide which can be absorbed systemically. Sulfonamides can produce severe, possibly fatal, reactions such as toxic epidermal necrolysis and Stevens-Johnson syndrome

FETAL TOXICITY

See full prescribing information for complete boxed warning.

Our database has 55 adverse reactions for this drug across the following areas

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SKIN
MUCOSAL
CARDIOVASCULAR
CENTRAL NERVOUS SYSTEM
NEUROMUSCULAR/SKELETAL
GASTROINTESTINAL/HEPATIC
RESPIRATORY
ENDOCRINE/METABOLIC
GENITOURINARY
HEMATOLOGIC
OTIC
OCULAR
OTHER


Page last updated 01/12/2017

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric