Gatifloxacin
- TRADE NAMES: Tequin (Bristol-Myers Squibb); Zymar (Allergan); Zymaxid (Allergan)
- INDICATIONS: Various infections caused by susceptible organisms
- CLASS: Antibiotic, Antibiotic; fluoroquinolone, Antimicrobial, Drug-resistant antituberculosis agent
- HALF-LIFE: 7–14 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Amiodarone, Arsenic, Asenapine, Bepridil, Bretylium, Disopyramide, Erythromycin, Phenothiazines, Pimavanserin, Procainamide, Quinidine, Sotalol, Tricyclic antidepressants, Zinc
PREGNANCY CATEGORY: C
Fluoroquinolones are associated with an increased risk of tendinitis and tendon rupture in all ages. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants.
Fluoroquinolones may exacerbate muscle weakness in persons with myasthenia gravis.
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SKIN.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
LOCAL.
NEUROMUSCULAR/SKELETAL.
OCULAR.
RESPIRATORY.
OTHER.
Page last updated 07/31/2023
Symbol key
Incidence
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric